Lingual Raynaud phenomenon

A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blu...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2015-10, Vol.187 (15), p.1160-1160
Main Authors: Ghiam, Alireza Fotouhi, Cho, John
Format: Article
Language:English
Subjects:
Care and treatment
Case studies
Clinical medicine
Development and progression
Female
Humans
Magnetic resonance imaging
Medical diagnosis
Medical imaging
Middle Aged
Patient outcomes
Practice
Raynaud disease
Raynaud Disease - diagnosis
Squamous cell carcinoma
Tongue - blood supply
Tongue - pathology
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Summary:A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blue discoloration of her tongue (Figure 1). These self-limiting episodes happened several times a day, apparently precipitated by cold weather or drinking cold drinks. She reported no tingling, pain or numbness. The symptoms did not involve her digits. There was no history of atherosclerotic or rheumatic disease, and she was not taking any medications used to treat Raynaud phenomenon.
ISSN:0820-3946
1488-2329
DOI:10.1503/cmaj.140784