Lingual Raynaud phenomenon

A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blu...

Full description

Saved in:
Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2015-10, Vol.187 (15), p.1160-1160
Main Authors: Ghiam, Alireza Fotouhi, Cho, John
Format: Article
Language:English
Subjects:
Care and treatment
Case studies
Clinical medicine
Development and progression
Female
Humans
Magnetic resonance imaging
Medical diagnosis
Medical imaging
Middle Aged
Patient outcomes
Practice
Raynaud disease
Raynaud Disease - diagnosis
Squamous cell carcinoma
Tongue - blood supply
Tongue - pathology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c640t-f11a95e033900aeaf0d6808c6a438a415108fe59a07ffd3a083a9a047f4c492c3
cites
container_end_page 1160
container_issue 15
container_start_page 1160
container_title Canadian Medical Association journal (CMAJ)
container_volume 187
creator Ghiam, Alireza Fotouhi
Cho, John
description A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blue discoloration of her tongue (Figure 1). These self-limiting episodes happened several times a day, apparently precipitated by cold weather or drinking cold drinks. She reported no tingling, pain or numbness. The symptoms did not involve her digits. There was no history of atherosclerotic or rheumatic disease, and she was not taking any medications used to treat Raynaud phenomenon.
doi_str_mv 10.1503/cmaj.140784
format article
fullrecord <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4610842</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A431965928</galeid><sourcerecordid>A431965928</sourcerecordid><originalsourceid>FETCH-LOGICAL-c640t-f11a95e033900aeaf0d6808c6a438a415108fe59a07ffd3a083a9a047f4c492c3</originalsourceid><addsrcrecordid>eNqV0u9r1DAYB_AgirtNX_nOFzIciCI987NN3gzG0G1wKEx9HR7TpJejTW5NK9t_b86b8yr3xjSlJP3024Q8CL0geE4EZh9MB6s54biS_BGaES5lQRlVj9EMS4oLpnh5gA5TWuHcGK2eogNaEiVEpWbo5cKHZoT2-BruAoz18XppQ-zyHZ6hJw7aZJ_fP4_Q908fv51fFosvF1fnZ4vClBwPhSMElLCYMYUxWHC4LiWWpgTOJHAiCJbOCgW4cq5mgCWDPOCV44YratgROt3mrscfna2NDUMPrV73voP-Tkfwevom-KVu4k_NyxzNaQ54ex_Qx5vRpkF3PhnbthBsHJMmFRU4d84yPfmHruLYh7y930pIXknyVzXQWu2Di_m_ZhOqzzgjqhSKyqyKPaqxweZFxmCdz9MT_3qPN2t_o3fRfA_KV207b_amvpt8kM1gb4cGxpT01dfr_7Cfp_bNjl1aaIdliu04-BjSFL7fQtPHlHrrHk6OYL0pUL0pUL0t0Kxf7R72g_1TkewXpCrZow</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1725584781</pqid></control><display><type>article</type><title>Lingual Raynaud phenomenon</title><source>PubMed Central</source><creator>Ghiam, Alireza Fotouhi ; Cho, John</creator><creatorcontrib>Ghiam, Alireza Fotouhi ; Cho, John</creatorcontrib><description>A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blue discoloration of her tongue (Figure 1). These self-limiting episodes happened several times a day, apparently precipitated by cold weather or drinking cold drinks. She reported no tingling, pain or numbness. The symptoms did not involve her digits. There was no history of atherosclerotic or rheumatic disease, and she was not taking any medications used to treat Raynaud phenomenon.</description><identifier>ISSN: 0820-3946</identifier><identifier>EISSN: 1488-2329</identifier><identifier>DOI: 10.1503/cmaj.140784</identifier><identifier>PMID: 26195579</identifier><identifier>CODEN: CMAJAX</identifier><language>eng</language><publisher>Canada: Joule Inc</publisher><subject>Care and treatment ; Case studies ; Clinical medicine ; Development and progression ; Female ; Humans ; Magnetic resonance imaging ; Medical diagnosis ; Medical imaging ; Middle Aged ; Patient outcomes ; Practice ; Raynaud disease ; Raynaud Disease - diagnosis ; Squamous cell carcinoma ; Tongue - blood supply ; Tongue - pathology</subject><ispartof>Canadian Medical Association journal (CMAJ), 2015-10, Vol.187 (15), p.1160-1160</ispartof><rights>COPYRIGHT 2015 Joule Inc.</rights><rights>Copyright 8872147 Canada Inc. Oct 20, 2015</rights><rights>2015 8872147 Canada Inc. or its licensors 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c640t-f11a95e033900aeaf0d6808c6a438a415108fe59a07ffd3a083a9a047f4c492c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610842/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610842/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27915,27916,53782,53784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26195579$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ghiam, Alireza Fotouhi</creatorcontrib><creatorcontrib>Cho, John</creatorcontrib><title>Lingual Raynaud phenomenon</title><title>Canadian Medical Association journal (CMAJ)</title><addtitle>CMAJ</addtitle><description>A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blue discoloration of her tongue (Figure 1). These self-limiting episodes happened several times a day, apparently precipitated by cold weather or drinking cold drinks. She reported no tingling, pain or numbness. The symptoms did not involve her digits. There was no history of atherosclerotic or rheumatic disease, and she was not taking any medications used to treat Raynaud phenomenon.</description><subject>Care and treatment</subject><subject>Case studies</subject><subject>Clinical medicine</subject><subject>Development and progression</subject><subject>Female</subject><subject>Humans</subject><subject>Magnetic resonance imaging</subject><subject>Medical diagnosis</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Patient outcomes</subject><subject>Practice</subject><subject>Raynaud disease</subject><subject>Raynaud Disease - diagnosis</subject><subject>Squamous cell carcinoma</subject><subject>Tongue - blood supply</subject><subject>Tongue - pathology</subject><issn>0820-3946</issn><issn>1488-2329</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqV0u9r1DAYB_AgirtNX_nOFzIciCI987NN3gzG0G1wKEx9HR7TpJejTW5NK9t_b86b8yr3xjSlJP3024Q8CL0geE4EZh9MB6s54biS_BGaES5lQRlVj9EMS4oLpnh5gA5TWuHcGK2eogNaEiVEpWbo5cKHZoT2-BruAoz18XppQ-zyHZ6hJw7aZJ_fP4_Q908fv51fFosvF1fnZ4vClBwPhSMElLCYMYUxWHC4LiWWpgTOJHAiCJbOCgW4cq5mgCWDPOCV44YratgROt3mrscfna2NDUMPrV73voP-Tkfwevom-KVu4k_NyxzNaQ54ex_Qx5vRpkF3PhnbthBsHJMmFRU4d84yPfmHruLYh7y930pIXknyVzXQWu2Di_m_ZhOqzzgjqhSKyqyKPaqxweZFxmCdz9MT_3qPN2t_o3fRfA_KV207b_amvpt8kM1gb4cGxpT01dfr_7Cfp_bNjl1aaIdliu04-BjSFL7fQtPHlHrrHk6OYL0pUL0pUL0t0Kxf7R72g_1TkewXpCrZow</recordid><startdate>20151020</startdate><enddate>20151020</enddate><creator>Ghiam, Alireza Fotouhi</creator><creator>Cho, John</creator><general>Joule Inc</general><general>CMA Impact, Inc</general><general>8872147 Canada Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ISN</scope><scope>ISR</scope><scope>3V.</scope><scope>4T-</scope><scope>4U-</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FQ</scope><scope>8FV</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M3G</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20151020</creationdate><title>Lingual Raynaud phenomenon</title><author>Ghiam, Alireza Fotouhi ; Cho, John</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c640t-f11a95e033900aeaf0d6808c6a438a415108fe59a07ffd3a083a9a047f4c492c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Care and treatment</topic><topic>Case studies</topic><topic>Clinical medicine</topic><topic>Development and progression</topic><topic>Female</topic><topic>Humans</topic><topic>Magnetic resonance imaging</topic><topic>Medical diagnosis</topic><topic>Medical imaging</topic><topic>Middle Aged</topic><topic>Patient outcomes</topic><topic>Practice</topic><topic>Raynaud disease</topic><topic>Raynaud Disease - diagnosis</topic><topic>Squamous cell carcinoma</topic><topic>Tongue - blood supply</topic><topic>Tongue - pathology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghiam, Alireza Fotouhi</creatorcontrib><creatorcontrib>Cho, John</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Canada</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Health &amp; Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Canadian Business &amp; Current Affairs Database</collection><collection>Canadian Business &amp; Current Affairs Database (Alumni Edition)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>British Nursing Index</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>ProQuest Health Management Database</collection><collection>PML(ProQuest Medical Library)</collection><collection>Psychology Database (ProQuest)</collection><collection>ProQuest research library</collection><collection>ProQuest Science Journals</collection><collection>CBCA Reference &amp; Current Events</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian Medical Association journal (CMAJ)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghiam, Alireza Fotouhi</au><au>Cho, John</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lingual Raynaud phenomenon</atitle><jtitle>Canadian Medical Association journal (CMAJ)</jtitle><addtitle>CMAJ</addtitle><date>2015-10-20</date><risdate>2015</risdate><volume>187</volume><issue>15</issue><spage>1160</spage><epage>1160</epage><pages>1160-1160</pages><issn>0820-3946</issn><eissn>1488-2329</eissn><coden>CMAJAX</coden><abstract>A 45-year-old woman with squamous cell carcinoma of her right tonsil (stage T2N2bM0) was given accelerated fractionated radiotherapy (7000 cGy in 35 fractions over 6 wk), concurrently with cetuximab. After completing radiotherapy, she did well for 18 months, when she had intermittent episodes of blue discoloration of her tongue (Figure 1). These self-limiting episodes happened several times a day, apparently precipitated by cold weather or drinking cold drinks. She reported no tingling, pain or numbness. The symptoms did not involve her digits. There was no history of atherosclerotic or rheumatic disease, and she was not taking any medications used to treat Raynaud phenomenon.</abstract><cop>Canada</cop><pub>Joule Inc</pub><pmid>26195579</pmid><doi>10.1503/cmaj.140784</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0820-3946
ispartof Canadian Medical Association journal (CMAJ), 2015-10, Vol.187 (15), p.1160-1160
issn 0820-3946
1488-2329
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4610842
source PubMed Central
subjects Care and treatment
Case studies
Clinical medicine
Development and progression
Female
Humans
Magnetic resonance imaging
Medical diagnosis
Medical imaging
Middle Aged
Patient outcomes
Practice
Raynaud disease
Raynaud Disease - diagnosis
Squamous cell carcinoma
Tongue - blood supply
Tongue - pathology
title Lingual Raynaud phenomenon
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T21%3A33%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lingual%20Raynaud%20phenomenon&rft.jtitle=Canadian%20Medical%20Association%20journal%20(CMAJ)&rft.au=Ghiam,%20Alireza%20Fotouhi&rft.date=2015-10-20&rft.volume=187&rft.issue=15&rft.spage=1160&rft.epage=1160&rft.pages=1160-1160&rft.issn=0820-3946&rft.eissn=1488-2329&rft.coden=CMAJAX&rft_id=info:doi/10.1503/cmaj.140784&rft_dat=%3Cgale_pubme%3EA431965928%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c640t-f11a95e033900aeaf0d6808c6a438a415108fe59a07ffd3a083a9a047f4c492c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1725584781&rft_id=info:pmid/26195579&rft_galeid=A431965928&rfr_iscdi=true