Pulmonary infection with Nocardia caviae in a patient with diabetes mellitus and liver cirrhosis

The first reported case of pulmonary infection with Nocardia caviae in Britain occurred in a 67 year old woman, in whom diabetes mellitus and liver cirrhosis probably contributed to impaired cell mediated immunity. She was successfully treated with gentamicin 60 mg eight hourly and sulphadimidine 50...

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Bibliographic Details
Published in:Thorax 1988-11, Vol.43 (11), p.933-934
Main Authors: Salh, B, Fegan, C, Hussain, A, Jaulim, A, Whale, K, Webb, A
Format: Article
Language:English
Subjects:
Aged
Bacterial diseases
Bacterial diseases of the respiratory system
Biological and medical sciences
Diabetes Complications
Drug Therapy, Combination
Female
Gentamicins - therapeutic use
Human bacterial diseases
Humans
Infectious diseases
Liver Cirrhosis - complications
Lung Diseases - complications
Lung Diseases - drug therapy
Medical sciences
Nocardia Infections - complications
Nocardia Infections - drug therapy
Sulfamethazine - therapeutic use
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Summary:The first reported case of pulmonary infection with Nocardia caviae in Britain occurred in a 67 year old woman, in whom diabetes mellitus and liver cirrhosis probably contributed to impaired cell mediated immunity. She was successfully treated with gentamicin 60 mg eight hourly and sulphadimidine 500 mg six hourly for six months and then with sulphadimidine 2 g/day for a further three months. When Nocardia caviae is isolated from the sputum of a patient with chronic respiratory infection and fever, effective treatment should be started promptly.
ISSN:0040-6376
1468-3296
DOI:10.1136/thx.43.11.933