Renal-type clear cell carcinoma of the prostate: a diagnostic challenge

A 72-year-old male presented with urinary symptoms. His serum prostate specific antigen level was 65.2 ng/ml. His radical prostatectomy specimen showed clear cell lesion reminiscent of the clear cell renal cell carcinoma along with acinar type of prostatic adenocarcinoma, Gleason score 4 + 4. The le...

Full description

Saved in:
Bibliographic Details
Published in:Diagnostic pathology 2015-10, Vol.10 (1), p.193-193, Article 193
Main Authors: Patne, Shashikant C U, Johri, Nidhi, Katiyar, Richa, Trivedi, Sameer, Dwivedi, Uday Shankar
Format: Article
Language:English
Subjects:
Adenocarcinoma - diagnosis
Adenocarcinoma - surgery
Aged
Biomarkers, Tumor - analysis
Cancer
Carcinoma
Carcinoma, Renal Cell - diagnosis
Carcinoma, Renal Cell - surgery
Care and treatment
Case Report
Case studies
Development and progression
Diagnosis
Humans
Immunohistochemistry - methods
Kidney Neoplasms - pathology
Kidney Neoplasms - surgery
Male
Metastasis
Neoplasms, Multiple Primary - diagnosis
Neoplasms, Multiple Primary - surgery
Patient outcomes
Prostate cancer
Prostate-specific antigen
Prostate-Specific Antigen - metabolism
Prostatectomy - methods
Prostatic Neoplasms - metabolism
Prostatic Neoplasms - pathology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 72-year-old male presented with urinary symptoms. His serum prostate specific antigen level was 65.2 ng/ml. His radical prostatectomy specimen showed clear cell lesion reminiscent of the clear cell renal cell carcinoma along with acinar type of prostatic adenocarcinoma, Gleason score 4 + 4. The lesional clear cells were positive for pancytokeratin, epithelial membrane antigen, CD10, vimentin, and AMACR while negative for 34βE12, CK7, prostate specific antigen, and PAX8. The final diagnosis was renal-type clear cell carcinoma of the prostate. A follow-up of 20 months did not show metastasis. We herein report fifth case of renal-type clear cell carcinoma of the prostate.
ISSN:1746-1596
1746-1596
DOI:10.1186/s13000-015-0432-8