Additive effect of linseed oil supplementation on the lipid profiles of older adults

Linseed oil has been investigated as a rich source of n-3 series polyunsaturated fatty acids, which mainly produce a non-atherogenic lipid profile. The objective of this study was to investigate the effect of linseed oil supplementation associated with nutritional guidelines on the lipid profiles of...

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Bibliographic Details
Published in:Clinical interventions in aging 2015-01, Vol.10, p.1679-1685
Main Authors: Avelino, Ana Paula A, Oliveira, Gláucia M M, Ferreira, Célia C D, Luiz, Ronir R, Rosa, Glorimar
Format: Article
Language:English
Subjects:
Aged
Analysis
Anthropometry
Atherosclerosis
Body Composition
Brazil
Cardiovascular disease
Care and treatment
Complications and side effects
Dietary Supplements
Double-Blind Method
Elderly
Fatty Acids - administration & dosage
Female
Health aspects
Humans
Linseed oil
Linseed Oil - pharmacology
Lipids
Lipids - blood
Male
Middle Aged
Nutritional requirements
Older people
Original Research
Polyunsaturated fatty acids
Prospective Studies
Systematic review
Treatment Outcome
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Summary:Linseed oil has been investigated as a rich source of n-3 series polyunsaturated fatty acids, which mainly produce a non-atherogenic lipid profile. The objective of this study was to investigate the effect of linseed oil supplementation associated with nutritional guidelines on the lipid profiles of older adults, according to the intake of saturated fatty acids (SFA). We conducted a double-blind, placebo-controlled clinical trial with 110 older adults randomized in two groups: placebo and linseed oil. The linseed oil group received supplementation with 3 g of linseed oil. Both groups received nutritional guidance and were supplemented for 90 days with monthly blood collection for biochemical analysis. The dietary intake of saturated fat was subdivided into low (7% SFA/day of the total energy value). Low SFA (7% SFA/day, had a greater reduction in total cholesterol than the placebo group (P=0.020). The same was observed for low-density lipoprotein (LDL) cholesterol (P
ISSN:1178-1998
1176-9092
1178-1998
DOI:10.2147/CIA.S75538