Long-Term Renal Function after Endovascular Aneurysm Repair

Endovascular repair (EVAR) is a common treatment for abdominal aortic aneurysm (AAA). However, its long-term effects on renal function remain unclear. We aimed to assess long-term renal dysfunction after EVAR using a contemporary estimate of GFR and to compare long-term renal outcomes in patients af...

Full description

Saved in:
Bibliographic Details
Published in:Clinical journal of the American Society of Nephrology 2015-11, Vol.10 (11), p.1930-1936
Main Authors: Saratzis, Athanasios, Bath, Michael F, Harrison, Seamus, Sayers, Robert D, Mahmood, Asif, Sarafidis, Pantelis, Bown, Matthew J
Format: Article
Language:English
Subjects:
Aortic Aneurysm, Abdominal - surgery
Endovascular Procedures
Humans
Kidney - physiology
Original
Time Factors
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Endovascular repair (EVAR) is a common treatment for abdominal aortic aneurysm (AAA). However, its long-term effects on renal function remain unclear. We aimed to assess long-term renal dysfunction after EVAR using a contemporary estimate of GFR and to compare long-term renal outcomes in patients after EVAR with open aneurysm repair (OAR) and in patients without an AAA. We performed a nested case-matched analysis of 726 patients (using a prospectively maintained database for repairs that took place between January 2000 and May 2010 in a tertiary center): 121 patients undergoing OAR (with data at baseline and 5 years postrepair) were case matched (age, sex, smoking, diabetes, baseline eGFR) to patients undergoing suprarenal and infrarenal fixation EVAR (242 in each group) and to 121 patients undergoing carotid endarterectomy (CEA) without AAA. Changes in eGFR were compared (1 and 5 years). The OAR patients lost an average of 7.4 ml/min per 1.73 m2 at 5 years (95% confidence interval [95% CI], 4.8 to 10.6), compared with 8.2 ml/min per 1.73 m2 (95% CI, 6.5 to 10.8; P
ISSN:1555-9041
1555-905X
DOI:10.2215/cjn.04870515