Multiple organ dysfunction syndrome, an unusual complication of heroin intoxication: a case report and review of literature

Multiple organ dysfunction syndrome (MODS) has rarely been described in patients with heroin intoxication. Here, we report a rare case of MODS involving six organs, due to heroin intoxication. The patient was a 32-year-old Chinese man with severe heroin intoxication complicated by acute pulmonary ed...

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Bibliographic Details
Published in:International journal of clinical and experimental pathology 2015-01, Vol.8 (9), p.11826-11830
Main Authors: Feng, Gang, Luo, Qiancheng, Guo, Enwei, Yao, Yulan, Yang, Feng, Zhang, Bingyu, Li, Longxuan
Format: Article
Language:English
Subjects:
Adult
Analgesics, Opioid - poisoning
Case Report
Heroin - poisoning
Heroin Dependence - complications
Heroin Dependence - diagnosis
Humans
Male
Multiple Organ Failure - chemically induced
Multiple Organ Failure - diagnosis
Multiple Organ Failure - therapy
Tomography, X-Ray Computed
Treatment Outcome
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Summary:Multiple organ dysfunction syndrome (MODS) has rarely been described in patients with heroin intoxication. Here, we report a rare case of MODS involving six organs, due to heroin intoxication. The patient was a 32-year-old Chinese man with severe heroin intoxication complicated by acute pulmonary edema and respiratory insufficiency, shock, myocardial damage and cardiac insufficiency, rhabdomyolysis and acute renal insufficiency, acute liver injury and hepatic insufficiency, toxic leukoencephalopathy, and hypoglycemia. He managed to survive and was discharged after 10 weeks of intensive care. The possible pathogenesis and therapeutic measures of MODS induced by heroin intoxication and some suggestions for preventing and treating severe complications of heroin intoxication, based on clinical evidence and the pertinent literature, are discussed in this report.
ISSN:1936-2625