Myopia Control with a Novel Peripheral Gradient Soft Lens and Orthokeratology: A 2-Year Clinical Trial

• Published in: BioMed research international 2015-01, Vol.2015 (2015), p.1-10
• Main Authors: Faria-Ribeiro, M., Quevedo, Lluisa, Armengol, Jesús, Morales, Hari, Pauné, Jaime, González-Méijome, J. M.
• Format: Article
• Language: English
• Subjects: Acomodació i refracció; Adolescent; Biomedical research; Child; Ciències de la salut; Ciències de la visió; Clinical Study; Clinical trials; Contact lenses; Contact Lenses, Hydrophilic; Contactologia; Eye; Female; Humans; Lents de contacte; Male; Medicina; Methods; Miopia; Myopia; Myopia - physiopathology; Myopia - therapy; Oftalmologia; Prevention; Prospective Studies; Refractive errors; Ulls; Àrees temàtiques de la UPC
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2015/507572

Objective. To evaluate the degree of axial elongation with soft radial refractive gradient (SRRG) contact lenses, orthokeratology (OK), and single vision (SV) spectacle lenses (control) during a period of 1 year before treatment and 2 years after treatment. Methods. This was a prospective, longitudinal, nonrandomized study. The study groups consisted of 30, 29, and 41 children, respectively. The axial length (AL) was measured during 2 years after recruitment and lens fitting. Results. The baseline refractive sphere was correlated significantly (Spearman’s Rho (ρ) correlation = 0.542; P < 0.0001) with the amount of myopia progression before baseline. After 2 years, the mean myopia progression values for the SRRG, OK, and SV groups were −0.56 ± 0.51, −0.32 ± 0.53, and −0.98 ± 0.58 diopter, respectively. The results represent reductions in myopic progression of 43% and 67% for the SRRG and OK groups, respectively, compared to the SV group. The AL increased 27% and 38% less in the SRRG and OK groups, respectively compared with the SV group at the 2-year visit (P < 0.05). Axial elongation was not significantly different between SRRG and OK (P = 0.430). Conclusion. The SRRG lens significantly decreased AL elongation compared to the SV control group. The SRRG lens was similarly effective to OK in preventing myopia progression in myopic children and adolescent.