Neonatal idiopathic primary hypoparathyroidism: A rare cause of neonatal seizures

Etiology of neonatal seizures (NNS) is diverse and hypocalcemia is one of the treatable causes. Neonatal hypocalcemia (NHC) due to congenital hypoparathyroidism, either permanent or transient, is extremely rare. Its biochemical abnormalities include hypocalcemia, hyperphosphatemia and low levels of...

Full description

Saved in:
Bibliographic Details
Published in:Pakistan journal of medical sciences 2015-10, Vol.31 (5), p.1277-1279
Main Authors: Hussain, Shabbir, Sabir, Moin-Ud-Din, Ali, Mubaral, Shah, Syed Awais-Ul-Hassan
Format: Article
Language:English
Subjects:
Case Report
Genetic disorders
Hypoparathyroidism
Newborn infants
Parathyroid hormones
Seizures (Medicine)
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Etiology of neonatal seizures (NNS) is diverse and hypocalcemia is one of the treatable causes. Neonatal hypocalcemia (NHC) due to congenital hypoparathyroidism, either permanent or transient, is extremely rare. Its biochemical abnormalities include hypocalcemia, hyperphosphatemia and low levels of intact parathyroid hormone (PTH). Isolated congenital hypoparathyroidism in which deficiency of PTH has no association with maternal, syndromic or endocrine defects is a very rare entity. We are reporting a case of a newborn who presented with seizures on the 5th day of life and later on investigations revealed hypocalcaemia due to isolated congenital hypoparathyroidism.
ISSN:1682-024X
1681-715X
DOI:10.12669/pjms.315.7807