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Writing in the granular gel medium

Gels made from soft microscale particles smoothly transition between the fluid and solid states, making them an ideal medium in which to create macroscopic structures with microscopic precision. While tracing out spatial paths with an injection tip, the granular gel fluidizes at the point of injecti...

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Bibliographic Details
Published in:Science advances 2015-09, Vol.1 (8), p.e1500655-e1500655
Main Authors: Bhattacharjee, Tapomoy, Zehnder, Steven M, Rowe, Kyle G, Jain, Suhani, Nixon, Ryan M, Sawyer, W Gregory, Angelini, Thomas E
Format: Article
Language:English
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Summary:Gels made from soft microscale particles smoothly transition between the fluid and solid states, making them an ideal medium in which to create macroscopic structures with microscopic precision. While tracing out spatial paths with an injection tip, the granular gel fluidizes at the point of injection and then rapidly solidifies, trapping injected material in place. This physical approach to creating three-dimensional (3D) structures negates the effects of surface tension, gravity, and particle diffusion, allowing a limitless breadth of materials to be written. With this method, we used silicones, hydrogels, colloids, and living cells to create complex large aspect ratio 3D objects, thin closed shells, and hierarchically branched tubular networks. We crosslinked polymeric materials and removed them from the granular gel, whereas uncrosslinked particulate systems were left supported within the medium for long times. This approach can be immediately used in diverse areas, contributing to tissue engineering, flexible electronics, particle engineering, smart materials, and encapsulation technologies.
ISSN:2375-2548
2375-2548
DOI:10.1126/sciadv.1500655