To counteract or to clear high-mobility group box-1 protein in influenza A (H1N1) infection? That may become the question

The clinical course of influenza infection is usually severe in infants, as in the 2009 pandemic. [...]young children should be focused on when preparing for future influenza outbreaks. [...]CRRT is difficult to administer to children, especially those less than 10 kg, because of the lack of trained...

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Bibliographic Details
Published in:Critical care (London, England) England), 2015-11, Vol.19 (401), p.401-401, Article 401
Main Authors: Honore, Patrick M, Jacobs, Rita, Hendrickx, Inne, De Waele, Elisabeth, Van Gorp, Viola, Spapen, Herbert D
Format: Article
Language:English
Subjects:
Acute respiratory distress syndrome
Animals
Antibodies, Monoclonal - administration & dosage
Care and treatment
Complications and side effects
Critical care
HMGB1 Protein - antagonists & inhibitors
Infections
Influenza
Influenza A Virus, H1N1 Subtype - drug effects
Intensive care
Intensive care units
Letter
Male
Membranes
Molecular weight
Mortality
Orthomyxoviridae Infections - drug therapy
Pandemics
Pneumonia
Pneumonia, Viral - drug therapy
Proteins
Respiratory distress syndrome
Respiratory therapy
Risk factors
Sepsis
Services
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Summary:The clinical course of influenza infection is usually severe in infants, as in the 2009 pandemic. [...]young children should be focused on when preparing for future influenza outbreaks. [...]CRRT is difficult to administer to children, especially those less than 10 kg, because of the lack of trained staff or appropriate equipment [5].
ISSN:1364-8535
1466-609X
1364-8535
1366-609X
DOI:10.1186/s13054-015-1126-z