A supramolecular dissociation strategy for protein sensing

We report a simple, robust, and general strategy for protein detection based on supramolecular dissociation. The simplicity of the design is exemplified by the fact that the host assemblies can be widely varied and that these assemblies can be achieved from commercially available surfactants. An ope...

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2015-12, Vol.51 (97), p.17265-17268
Main Authors: Wang, Hui, Zhuang, Jiaming, Raghupathi, Krishna R, Thayumanavan, S
Format: Article
Language:English
Subjects:
Assemblies
Carbonic Anhydrase I - chemistry
Detection
Fluorescent Dyes - chemistry
Humans
Proteins
Proteins - chemistry
Spectrometry, Fluorescence
Strategy
Surfactants
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Summary:We report a simple, robust, and general strategy for protein detection based on supramolecular dissociation. The simplicity of the design is exemplified by the fact that the host assemblies can be widely varied and that these assemblies can be achieved from commercially available surfactants. An operating mechanism that is consistent with all the data has been proposed.
ISSN:1359-7345
1364-548X
DOI:10.1039/c5cc07408h