Weight loss therapy for clinical management of patients with some atherosclerotic diseases: a randomized clinical trial

The prevalence and burden of atherosclerotic (AS) diseases are increasing during the last twenty years. Some studies show a close relationship between overweight and AS, but influence on AS diseases of different weight loss methods are still studying. The purpose of the research was to study the eff...

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Bibliographic Details
Published in:Nutrition journal 2015-11, Vol.14 (1), p.120-120, Article 120
Main Authors: Oshakbayev, Kuat, Dukenbayeva, Bibazhar, Otarbayev, Nurzhan, Togizbayeva, Gulnar, Tabynbayev, Nariman, Gazaliyeva, Meruyert, Idrisov, Alisher, Oshakbayev, Pernekul
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Atherosclerosis
Atherosclerosis - complications
Caloric Restriction - methods
Care and treatment
Diet, Fat-Restricted - methods
Exercise
Female
Humans
Male
Methods
Middle Aged
Nutrition
Overweight - complications
Overweight - therapy
Prospective Studies
Treatment Outcome
Walking
Weight Loss
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Summary:The prevalence and burden of atherosclerotic (AS) diseases are increasing during the last twenty years. Some studies show a close relationship between overweight and AS, but influence on AS diseases of different weight loss methods are still studying. The purpose of the research was to study the effectiveness of a weight loss program in AS patients in randomized controlled trial, and to develop a conception of evolution of AS. A randomized controlled prospective clinical trial including 97 people, from them 71 patients with various AS manifestations. Patients were divided in 2 subgroups for non-drug weight loss program, and conventional drug therapy. The weight loss program included calorie restriction with 100-150 kcal/day, fat-free vegetables, salt diet, and optimum physical activity. Statistical analysis was performed using SPSS for Windows version 17.0. The weight loss subgroup lost ranging between 7-20% from an initial weight (P = 0.016). Weight loss was achieved due to fatty mass reduction only (P = 0.005). Hemoglobin levels (P 
ISSN:1475-2891
1475-2891
DOI:10.1186/s12937-015-0108-y