Intravascular large B-cell lymphoma involving gastrointestinal stromal tumor: a case report and literature review

Intravascular large B-cell lymphoma is a rare and aggressive lymphoma with a dismal prognosis. Synchronous intravascular large B-cell lymphoma involving gastrointestinal stromal tumor has not previously been documented. We report a case of a 61-year-old Chinese woman who presented with high fever of...

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Bibliographic Details
Published in:Diagnostic pathology 2015-12, Vol.10 (214), p.214-214, Article 214
Main Authors: Zhang, Fen, Luo, Xinlan, Chen, Yu, Liu, Yanhui
Format: Article
Language:English
Subjects:
Analysis
Biopsy
Bone marrow
Care and treatment
Case Report
Complications and side effects
Consent
Dehydrogenases
Female
Fever
Gastrointestinal Stromal Tumors
Hematology
Histochemistry
Humans
Lymphocytic leukemia
Lymphoma
Lymphoma, B-Cell - diagnosis
Lymphoma, B-Cell - pathology
Lymphoma, Non-Hodgkin - diagnosis
Lymphoma, Non-Hodgkin - pathology
Middle Aged
Morphology
Neoplasms, Multiple Primary - diagnosis
Neoplasms, Multiple Primary - pathology
Prognosis
Proteins
Risk factors
Stomach
Stomach cancer
Stomach Neoplasms - blood supply
Stomach Neoplasms - diagnosis
Stomach Neoplasms - pathology
Tomography, X-Ray Computed - methods
Ulcers
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Summary:Intravascular large B-cell lymphoma is a rare and aggressive lymphoma with a dismal prognosis. Synchronous intravascular large B-cell lymphoma involving gastrointestinal stromal tumor has not previously been documented. We report a case of a 61-year-old Chinese woman who presented with high fever of unknown origin for 20 days, and hematemesis, melena for 2 days. A computed tomography scan revealed a mass lesion located in the anterior wall of the stomach. Surgery was performed to remove the tumor and histopathology showed a gastrointestinal stromal tumor and a synchronous intravascular large B-cell lymphoma. The patient refused further treatment and died 4 months after surgery. To the best of our knowledge, this case represents the first report of synchronous intravascular large B-cell lymphoma involving a gastrointestinal stromal tumor.
ISSN:1746-1596
1746-1596
DOI:10.1186/s13000-015-0446-2