Lessons from Animal Models of Arterial Aneurysm

Abstract We review the results from the most common animal models of arterial aneurysm, including recent findings from our novel, laparoscopy-based pig model of abdominal aortic aneurysm, that contribute important insights into early pathogenesis. We emphasize the relevance of these findings for eva...

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Bibliographic Details
Published in:Aorta (Stamford, Conn.) Conn.), 2013-10, Vol.1 (5), p.244-254
Main Authors: Gertz, S. David, Mintz, Yoav, Beeri, Ronen, Rubinstein, Chen, Gilon, Dan, Gavish, Leah, Berlatzky, Yacov, Appelbaum, Liat, Gavish, Lilach
Format: Article
Language:English
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State-of-the-Art Review
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Summary:Abstract We review the results from the most common animal models of arterial aneurysm, including recent findings from our novel, laparoscopy-based pig model of abdominal aortic aneurysm, that contribute important insights into early pathogenesis. We emphasize the relevance of these findings for evaluation of treatment protocols and novel device prototypes for mechanism-based prevention of progression and rupture.
ISSN:2325-4637
2325-4637
DOI:10.12945/j.aorta.2013.13-052