Effects of Topical Kiwifruit on Healing of Chronic Bedsore

Kiwifruit ( Actindia deliciosa ) is demonstrated to have antibacterial and pro-angiogenic effect. Moreover, this fruit contains proteolytic enzymes (actinidin) and ascorbic acid. Considering these properties and based on the results of recent animal studies, we carried out this study to evaluate the...

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Bibliographic Details
Published in:Indian journal of surgery 2015-12, Vol.77 (Suppl 2), p.442-446
Main Authors: Mohajeri, Gholamreza, Safaee, Masoumeh, Sanei, Mohamad Hossein
Format: Article
Language:English
Subjects:
Antibacterial agents
Aspartic proteases
Cardiac Surgery
Collagen
Decubitus ulcer
Fruits
Medicine
Medicine & Public Health
Neurosurgery
Original
Original Article
Pediatric Surgery
Plastic Surgery
Pressure ulcers
Surgery
Thoracic Surgery
Wound care
Wound healing
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Summary:Kiwifruit ( Actindia deliciosa ) is demonstrated to have antibacterial and pro-angiogenic effect. Moreover, this fruit contains proteolytic enzymes (actinidin) and ascorbic acid. Considering these properties and based on the results of recent animal studies, we carried out this study to evaluate the effects of kiwifruit on bedsore in clinical settings. Forty patients with stage 2–3 sacral bedsores, preferably paraplegic, quadriplegic, and/or hemiplegic, were allocated into two groups of experiment and control. Under local anesthesia and sedation, ulcers of the experiment and control groups were dressed with pure extract of kiwifruit and normal saline, respectively, on a daily basis for 21 days. The ulcers were examined and photographed weekly. Pre- and postintervention biopsies were taken from the ulcers to perform microbiological and histological study. Mean reduction in surface area of bedsore in the experiment group was significantly higher than the control group (486.47 vs. 117.38 mm, p  
ISSN:0972-2068
0973-9793
DOI:10.1007/s12262-013-0869-5