Evaluation of the Lyra Direct Strep Assay To Detect Group A Streptococcus and Group C and G Beta-Hemolytic Streptococcus from Pharyngeal Specimens

The Lyra Direct strep assay was compared to culture for its ability to detect Streptococcus group A and β-hemolytic groups C/G using rapid antigen-negative pharyngeal specimens (n = 161). The Lyra assay correctly detected all β-hemolytic streptococci (group A, n = 19; group C/G, n = 5). In batch mod...

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Bibliographic Details
Published in:Journal of clinical microbiology 2016-01, Vol.54 (1), p.175-177
Main Authors: Boyanton, Jr, Bobby L, Darnell, Elizabeth M, Prada, Anne E, Hansz, Dana M, Robinson-Dunn, Barbara
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Bacteriological Techniques - methods
Bacteriology
Child
Child, Preschool
Female
Humans
Infant
Male
Middle Aged
Molecular Diagnostic Techniques - methods
Streptococcal Infections - diagnosis
Streptococcal Infections - microbiology
Streptococcus
Streptococcus - classification
Streptococcus - isolation & purification
Time Factors
Young Adult
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Summary:The Lyra Direct strep assay was compared to culture for its ability to detect Streptococcus group A and β-hemolytic groups C/G using rapid antigen-negative pharyngeal specimens (n = 161). The Lyra assay correctly detected all β-hemolytic streptococci (group A, n = 19; group C/G, n = 5). In batch mode, the Lyra assay reduced intralaboratory turnaround time by 60% (18.1 h versus 45.0 h) but increased hands-on time by 96% (3 min 16 s versus 1 min 40 s per specimen).
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.02405-15