Use and Abuse of Internal Cardioverter Defibrillators for Primary Prevention

Sudden cardiac death (SCD) is one of the leading causes of mortality in developed countries. Internal cardioverter defibrillators (ICDs) have been developed to treat potentially life-threatening ventricular arrhythmias. Multiple randomised trials have been completed to assess the efficacy of primary...

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Bibliographic Details
Published in:Arrhythmia & electrophysiology review 2012-09, Vol.1 (1), p.46-50
Main Authors: Silverstein, Joshua R, Katritsis, Demosthenes G, Josephson, Mark E
Format: Article
Language:English
Subjects:
Asymptomatic
Beta blockers
Cardiac arrhythmia
Cardiomyopathy
Cardiovascular disease
Coronary vessels
Defibrillators
Device Therapy
Heart attacks
Heart failure
Ischemia
Mortality
Prevention
Transplants & implants
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Description
Summary:Sudden cardiac death (SCD) is one of the leading causes of mortality in developed countries. Internal cardioverter defibrillators (ICDs) have been developed to treat potentially life-threatening ventricular arrhythmias. Multiple randomised trials have been completed to assess the efficacy of primary prevention ICDs in selected populations. In response to the randomised, controlled trials guidelines have been established to help guide physicians in choosing appropriate patients who may benefit from primary prevention ICDs. Unfortunately, many patients who currently fall within the guidelines are either not represented in the clinical trials or disregarded. The morbidity associated with ICD implant is also overlooked and the cost-benefit analyses are exaggerated in favour of ICD implant. This review article summarises major clinical trials addressing primary prevention ICDs, and also highlights the evidence supporting the use and abuse of ICDs.
ISSN:2050-3369
2050-3377
2050-3377
DOI:10.15420/aer.2012.1.46