The development of global vaccine stockpiles

Summary Global vaccine stockpiles, in which vaccines are reserved for use when needed for emergencies or supply shortages, have effectively provided countries with the capacity for rapid response to emergency situations, such as outbreaks of yellow fever and meningococcal meningitis. The high cost a...

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Bibliographic Details
Published in:The Lancet infectious diseases 2015-03, Vol.15 (3), p.340-347
Main Authors: Yen, Catherine, Dr, Hyde, Terri B, MD, Costa, Alejandro J, MSc, Fernandez, Katya, MSc, Tam, John S, PhD, Hugonnet, Stéphane, MD, Huvos, Anne M, JD, Duclos, Philippe, PhD, Dietz, Vance J, MD, Burkholder, Brenton T, MD
Format: Article
Language:English
Subjects:
Biological & chemical terrorism
Communicable Disease Control - methods
Communicable Diseases, Emerging - epidemiology
Communicable Diseases, Emerging - prevention & control
Disease prevention
Global Health
Humans
Immunization
Infectious Disease
Infectious diseases
Meningitis
Pandemics
Public health
Smallpox
Strategic Stockpile
Vaccines
Vaccines - supply & distribution
Vector-borne diseases
Waterborne diseases
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Summary:Summary Global vaccine stockpiles, in which vaccines are reserved for use when needed for emergencies or supply shortages, have effectively provided countries with the capacity for rapid response to emergency situations, such as outbreaks of yellow fever and meningococcal meningitis. The high cost and insufficient supply of many vaccines, including oral cholera vaccine and pandemic influenza vaccine, have prompted discussion on expansion of the use of vaccine stockpiles to address a wider range of emerging and re-emerging diseases. However, the decision to establish and maintain a vaccine stockpile is complex and must take account of disease and vaccine characteristics, stockpile management, funding, and ethical concerns, such as equity. Past experience with global vaccine stockpiles provide valuable information about the processes for their establishment and maintenance. In this Review we explored existing literature and stockpile data to discuss the lessons learned and to inform the development of future vaccine stockpiles.
ISSN:1473-3099
1474-4457
DOI:10.1016/S1473-3099(14)70999-5