Low grade gastric MALTOMA: Treatment strategies based on 10 year follow-up

AIM: To deduce strategic guideline of gastric mucosa associated lymphoid tissue lymphoma (MALTOMA) by evaluating the long-term outcome of patients in respect to various treatment modalities. METHODS: A total of 55 patients with MALTOMA from May 1992 to August 2002 were retrospectively reviewed. RESU...

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Bibliographic Details
Published in:World journal of gastroenterology : WJG 2004, Vol.10 (2), p.223-226
Main Authors: Lee, Sang Kil, Lee, Yong Chan, Chung, Jae Bock, Chon, Chae Yoon, Moon, Young Myoung, Kang, Jin Kyung, Park, In-Suh, Suh, Chang Ok, Yang, Woo Ik
Format: Article
Language:English
Subjects:
H Pylori
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Summary:AIM: To deduce strategic guideline of gastric mucosa associated lymphoid tissue lymphoma (MALTOMA) by evaluating the long-term outcome of patients in respect to various treatment modalities. METHODS: A total of 55 patients with MALTOMA from May 1992 to August 2002 were retrospectively reviewed. RESULTS: Complete remission was obtained in 24 (82.8%) of 29 patients treated with anti Helicobacter pylori ( H pylori) regimen only. The duration to reach complete remission was 12 months (85 percentile, 2-33 months). Five patients showed complete remission with radiation therapy (26-86 months). Two of them were H pylori treatment failure cases. CONCLUSION: H pylori eradication is an effective primary treatment option for low grade MALTOMA and radiation therapy could be considered in patients with no evidence of H pylori infection or who do not respond to H pylori eradication therapy 12 months after successful eradication.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v10.i2.223