Clinical analyses of endometriosis after conservative surgery

• Published in: International journal of clinical and experimental medicine 2015-01, Vol.8 (11), p.21703-21706
• Main Authors: Ke, Xiaoping, Qian, Haihong, Kang, Le, Wang, Jin, Xie, Yan, Cheng, Zhongping
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 1940-5901; 1940-5901

To assess the remission rate and outcome of pregnancy of patients who had moderate and severe ovarian endometriosis after conservative surgery. We also wished to analyze the associated factors of recurrence. Weconducted retrospective analyses of 199 cases with stage II-IV ovarian endometriosis who had preserved fertility under laparoscopic surgical treatment. Postoperatively, the 199 patients were divided into three groups: 43 cases underwent surgical treatment alone (group A); 47 were given a gonadotropin-releasing hormone agonist (GnRH-α) (group B), and 109 were given mifepristone (group C). Ten cases in group A were infertile, 26 cases in group B, and 38 cases in group C. All patients were followed up for 3 years. This study was approved by the Ethics Committee of Yangpu District Central Hospital. In groups A, B and C, the remission rate was 58.13%, 70.21% and 60.55% and the difference not significant (P=0.384); Recurrence rates were 27.90%, 12.76% and 24.77%, and the difference between them significant (P