Langerhans cell histiocytosis: Current concepts in dentistry and case report

Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their marrow precursors, resulting in localized, solitary or multiple destructive les...

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Published in:Journal of clinical and experimental dentistry 2016-02, Vol.8 (1), p.e102-e108
Main Authors: Ramos-Gutiérrez, Efraín, Alejo-González, Francisco, Ruiz-Rodríguez, Socorro, Garrocho-Rangel, José-Arturo, Pozos-Guillén, Amaury
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Case Report
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container_title Journal of clinical and experimental dentistry
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Alejo-González, Francisco
Ruiz-Rodríguez, Socorro
Garrocho-Rangel, José-Arturo
Pozos-Guillén, Amaury
description Langerhans cell histiocytosis (LCH), which is a rare granulomatous pediatric disease of unknown etiology, is characterized by the idiopathic proliferation and accumulation of abnormal and clonal Langerhans cells or their marrow precursors, resulting in localized, solitary or multiple destructive lesions. These lesions are most commonly eosinophilic granuloma, which are found in craniofacial bone structures such as the skull and mandible, skin and other organs. In children, the disease has a variable initial presentation, and the clinical course, prognosis and survival are unpredictable. The aims of this report were to present an LCH case in a girl aged 2 years, 8 months and her clinicopathological features, to describe the bucodental management provided, and to discuss special dental considerations of this disease. Children, dental management, histiocytosis, Langerhans cells.
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title Langerhans cell histiocytosis: Current concepts in dentistry and case report
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