Digital breast tomosynthesis within a symptomatic "one-stop breast clinic" for characterization of subtle findings

• Published in: British journal of radiology 2015-09, Vol.88 (1053), p.20140855-20140855
• Main Authors: Bansal, G J, Young, P
• Format: Article
• Language: English
• Subjects: Adult; Aged; Aged, 80 and over; Breast; Breast Neoplasms - diagnostic imaging; Early Detection of Cancer - methods; Female; Humans; Imaging, Three-Dimensional - methods; Mammography - methods; Middle Aged; Radiographic Image Enhancement - methods; Radiographic Image Interpretation, Computer-Assisted - methods; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed - methods
• ISSN: 0007-1285; 1748-880X
• DOI: 10.1259/bjr.20140855

The aim of the study was to evaluate the diagnostic accuracy of combination of full-field digital mammography [two dimension (2D)] and digital breast tomosynthesis [DBT, three dimension (3D)] by comparing the combination with 2D imaging in a symptomatic setting. A retrospective analysis was conducted involving 103 patients who attended symptomatic breast clinics between March 2012 and September 2012. All had subtle signs on 2D images or ultrasound. Mammographic score distribution was compared between 2D imaging and 2D + 3D imaging, followed by comparison with the gold-standard histopathology. Receiver operative characteristic curves and area under curve (AUC) were calculated for 2D imaging and the combination imaging (2D + 3D). SPSS(®) v. 21 (IBM Corp., New York, NY; formerly SPSS Inc., Chicago, IL) was used for data analysis with p