A Case of Advanced Extramammary Paget's Disease Successfully Controlled by Monthly but Not Weekly Docetaxel Chemotherapy

Extramammary Paget's disease (EMPD) is an uncommon cutaneous adenocarcinoma arising from the apocrine glands within the epidermis or underlying skin appendages in the anogenital and axillary regions. Surgical excision is basically performed as a treatment for EMPD. However, therapeutic options...

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Bibliographic Details
Published in:Case reports in oncology 2016-01, Vol.9 (1), p.6-10
Main Authors: Yoshihara, Yuki, Itoh, Munenari, Nobeyama, Yoshimasa, Nakagawa, Hidemi
Format: Article
Language:English
Subjects:
Chemotherapy
Docetaxel
Extramammary Paget's disease
Published: January 2016
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Summary:Extramammary Paget's disease (EMPD) is an uncommon cutaneous adenocarcinoma arising from the apocrine glands within the epidermis or underlying skin appendages in the anogenital and axillary regions. Surgical excision is basically performed as a treatment for EMPD. However, therapeutic options for EMPD in an advanced stage are limited. Herein, we report the case of a Japanese woman with advanced EMPD successfully controlled by monthly but not weekly docetaxel therapy. We also demonstrate the possibility that a monthly regimen of docetaxel is a more effective and optimal schedule than a weekly one through this case report.
ISSN:1662-6575
1662-6575
DOI:10.1159/000443234