Abnormalities of vascular structure and function in pediatric hypertension

Hypertension is associated with adverse cardiovascular (CV) events in adults. Measures of vascular structure and function, including increased carotid intima–media thickness (cIMT) and elevated arterial stiffness predict hard CV events in adulthood. Newer data suggest that abnormalities in target or...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2016-07, Vol.31 (7), p.1061-1070
Main Author: Urbina, Elaine M.
Format: Article
Language:English
Subjects:
Adolescent
Blood pressure
Cardiovascular diseases
Care and treatment
Carotid arteries
Carotid Intima-Media Thickness
Child
Complications and side effects
Diabetes
Educational Review
Health aspects
Humans
Hypertension
Hypertension - physiopathology
Kidney diseases
Medicine
Medicine & Public Health
Nephrology
Pediatrics
Risk factors
Teenagers
Urology
Vascular Stiffness - physiology
Veins & arteries
Young adults
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Description
Summary:Hypertension is associated with adverse cardiovascular (CV) events in adults. Measures of vascular structure and function, including increased carotid intima–media thickness (cIMT) and elevated arterial stiffness predict hard CV events in adulthood. Newer data suggest that abnormalities in target organ damage are occurring in adolescents and young adults with high blood pressure. In this review, we discuss the techniques for measuring vascular dysfunction in young people and the evidence linking blood pressure levels to this type of target organ damage.
ISSN:0931-041X
1432-198X
DOI:10.1007/s00467-015-3188-1