Sporicidal activity of hospital disinfectants

The sporicidal activity of hospital disinfectants was tested using two methods of test and two species of spores. Alcoholic hypochlorite and glutaraldehyde (Cidex) showed some sporicidal activity; the first was the more effective. Iodophors, formalin, and phenolics were less effective, in descending...

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Bibliographic Details
Published in:Journal of clinical pathology 1974-08, Vol.27 (8), p.632-638
Main Authors: Kelsey, J. C., Mackinnon, I. H., Maurer, Isobel M.
Format: Article
Language:English
Subjects:
Aldehydes - pharmacology
Bacillus subtilis
Cell Survival
Corrosion
Cross Infection - prevention & control
Disinfectants - pharmacology
Equipment and Supplies
Formaldehyde - pharmacology
Glutaral - pharmacology
Humans
Hydrocarbons, Iodinated - pharmacology
Phenols - pharmacology
Spores, Bacterial - drug effects
Sterilization
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Summary:The sporicidal activity of hospital disinfectants was tested using two methods of test and two species of spores. Alcoholic hypochlorite and glutaraldehyde (Cidex) showed some sporicidal activity; the first was the more effective. Iodophors, formalin, and phenolics were less effective, in descending order. Chlorhexidine showed no activity. A freshly prepared solution containing 50% methanol and sufficient sodium hypochlorite to provide 2000 parts per million available chlorine in distilled water, with a contact time of 15 minutes, is suggested for the decontamination of clean, heat-sensitive instruments except those of plated metal. It must be understood that no such method can be depended upon to sterilize. The instruments should be rinsed in sterile water before use after decontamination.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.27.8.632