Assessment of thyroid hormone assays

Four techniques for estimating serum T4 and three for estimating serum T3 have been investigated and found to be satisfactory in routine use. Normal ranges for each techniques have been established. Estimation of serum T3 by the commerical kits tested appears to have a high discriminant value in the...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical pathology 1976-12, Vol.29 (12), p.1054-1059
Main Authors: Evered, D C, Vice, P A, Green, E, Appleton, D
Format: Article
Language:English
Subjects:
Binding, Competitive
Female
Humans
Hyperthyroidism - diagnosis
Hypothyroidism - diagnosis
Methods
Pregnancy
Radioimmunoassay
Thyroid Hormones - blood
Thyroxine - blood
Triiodothyronine - blood
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Four techniques for estimating serum T4 and three for estimating serum T3 have been investigated and found to be satisfactory in routine use. Normal ranges for each techniques have been established. Estimation of serum T3 by the commerical kits tested appears to have a high discriminant value in the diagnosis of hyperthyroidism, although the diagnostic definition used inevitably enhances the apparent sensitivity of these techniques. Estimation of serum T4 will identify the majority of patients with symptomatic hypothyroidism. The low sensitivity of T3 in the diagnosis of thyroid failure is confirmed.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.29.12.1054