A modified rubella HI test using prestandardized reagents

A modified haemagglutination inhibition test for rubella antibodies using prestandardized freeze-dried reagents was compared to a "standard" method. Tests of 707 serum samples showed that the modified test was sensitive and reliable by both macrotitration and microtitration techniques. The...

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Bibliographic Details
Published in:Journal of clinical pathology 1976-12, Vol.29 (12), p.1101-1104
Main Authors: Urquhart, G E, Worswick, D A, Grist, N R
Format: Article
Language:English
Subjects:
Antibodies, Viral - analysis
Hemagglutination Inhibition Tests - methods
Humans
Rubella - diagnosis
Rubella virus - immunology
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Description
Summary:A modified haemagglutination inhibition test for rubella antibodies using prestandardized freeze-dried reagents was compared to a "standard" method. Tests of 707 serum samples showed that the modified test was sensitive and reliable by both macrotitration and microtitration techniques. The minor disadvantages of some reduction in antibody level when rubella sera were tested within one week of the rash and of spontaneous sheep erythrocyte agglutination in 0-7% of sera were out-weighed by the increased speed of the new test and the fact that it was carried out at room temperature.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.29.12.1101