Clinical and Molecular Characterization of Invasive Heteroresistant Vancomycin-Intermediate Staphylococcus aureus Infections in Korean Hospitals

Invasive heteroresistant vancomycin-intermediate Staphylococcus aureus (h-VISA) isolates were identified and characterized in 10 Korean hospitals from July 2009 to June 2011. The prevalence of h-VISA infections was 3.3% (42/1,289). Most (41/42) were health care-associated infections caused by strain...

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Bibliographic Details
Published in:Journal of clinical microbiology 2016-03, Vol.54 (3), p.760-763
Main Authors: Kim, Eu Suk, Bae, In-Gyu, Cho, Jeong Eun, Choi, Yun Jung, Kim, Il-Hwan, Kang, Gi-Su, Sin, Hye-yun, Song, Kyoung-Ho, Park, Chulmin, Lee, Dong-Gun, Kim, Moonsuk, Park, Kyoung Un, Kim, Hong Bin
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Aged, 80 and over
Anti-Bacterial Agents - pharmacology
Bacteriology
Cross Infection
Female
Hospitals
Humans
Male
Microbial Sensitivity Tests
Middle Aged
Republic of Korea - epidemiology
Staphylococcal Infections - diagnosis
Staphylococcal Infections - epidemiology
Staphylococcal Infections - microbiology
Staphylococcus aureus - drug effects
Staphylococcus aureus - genetics
Vancomycin Resistance
Young Adult
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Summary:Invasive heteroresistant vancomycin-intermediate Staphylococcus aureus (h-VISA) isolates were identified and characterized in 10 Korean hospitals from July 2009 to June 2011. The prevalence of h-VISA infections was 3.3% (42/1,289). Most (41/42) were health care-associated infections caused by strains belonging to sequence type 5. Cases of persistent bacteremia were frequent (17/42), and 30-day mortality was high (16/40).
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.02595-15