High prevalence of being Overweight and Obese HIV-infected persons, before and after 24 months on early ART in the ANRS 12136 Temprano Trial

HIV is usually associated with weight loss. World health Organization (WHO) recommends early antiretroviral (ART) initiation, but data on the progression of body mass index (BMI) in participants initiating early ART in Africa are scarce. The Temprano randomized trial was conducted in Abidjan to asse...

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Bibliographic Details
Published in:AIDS research and therapy 2016-02, Vol.13 (12), p.12-12, Article 12
Main Authors: Guehi, Calixte, Badjé, Anani, Gabillard, Delphine, Ouattara, Eric, Koulé, Serge Olivier, Moh, Raoul, Ekouevi, Didier, Ahibo, Hugues, N'Takpé, Jean Baptiste, Menan, Gérard Kouamé, Deschamps, Nina, Lecarrou, Jerôme, Eholié, Serge, Anglaret, Xavier, Danel, Christine
Format: Article
Language:English
Subjects:
Adult
AIDS/HIV
Analysis
Anti-HIV Agents - therapeutic use
Antiretroviral drugs
Antitubercular Agents - therapeutic use
Antiviral agents
Body Mass Index
Clinical trials
Cote d'Ivoire - epidemiology
Drug therapy
Female
Health aspects
HIV
HIV Infections - complications
HIV Infections - drug therapy
Human immunodeficiency virus
Humans
Isoniazid - therapeutic use
Life Sciences
Male
Obesity
Obesity - complications
Obesity - epidemiology
Overweight - complications
Overweight - epidemiology
Tuberculosis, Pulmonary - prevention & control
Weight
Weight Loss - drug effects
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Summary:HIV is usually associated with weight loss. World health Organization (WHO) recommends early antiretroviral (ART) initiation, but data on the progression of body mass index (BMI) in participants initiating early ART in Africa are scarce. The Temprano randomized trial was conducted in Abidjan to assess the effectiveness of early ART and Isoniazid (INH) prophylaxis for tuberculosis in HIV-infected persons with high CD4 counts below 800 cells/mm(3) without any indication for starting ART. Patients initiating early ART before December 2010 were included in this sub-study. BMI was categorized as: underweight (
ISSN:1742-6405
1742-6405
DOI:10.1186/s12981-016-0094-y