Primary parietal myeloid sarcoma

Intracranial occurrence of myeloid sarcoma without any evidence of systemic hematological disorder is uncommon. We report the case of a 17-year-old girl who presented with features of raised intracranial pressure and paraparesis of short duration. Magnetic resonance imaging showed a 6 cm bilateral m...

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Bibliographic Details
Published in:Journal of pediatric neurosciences 2015-10, Vol.10 (4), p.389-392
Main Authors: Sivaraju, Laxminadh, Mohan, Dilip, Ghosal, Nandita, Nandeesh, Bevinahalli N, Hegde, Alangar S
Format: Article
Language:English
Subjects:
Analysis
Care and treatment
Case Report
Complications and side effects
Immunohistochemistry
Myeloid leukemia
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Summary:Intracranial occurrence of myeloid sarcoma without any evidence of systemic hematological disorder is uncommon. We report the case of a 17-year-old girl who presented with features of raised intracranial pressure and paraparesis of short duration. Magnetic resonance imaging showed a 6 cm bilateral middle 1/3(rd) para sagittal contrast enhancing extra-axial mass with mass effect. The tumor was subtotally excised. Histology and immunohistochemistry proved to be a myelosarcoma. Further evaluation done with peripheral blood smear and bone marrow biopsy ruled out the possibility of leukemia or myeloproliferative disorder. She was referred for chemotherapy and clinically showed improvement after 6 months of follow-up. Authors report a case of intracranial myelosarcoma which closely resembled meningioma both radiologically and in intraoperative morphological appearance. Authors discuss in detail the radiological and histological features of myelosarcoma along with differential diagnoses and treatment options.
ISSN:1817-1745
1998-3948
DOI:10.4103/1817-1745.174431