The isolation of enteroviruses from cases of acute conjunctivitis

In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the seco...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical pathology 1973-09, Vol.26 (9), p.706-711
Main Authors: Higgins, P. G., Scott, R. J. D.
Format: Article
Language:English
Subjects:
Animals
Conjunctivitis - diagnosis
Conjunctivitis - microbiology
Embryo, Mammalian
England
Enterovirus - isolation & purification
Epithelium - embryology
Epithelium - microbiology
Haplorhini
Humans
Indonesia
Intestines - embryology
Intestines - microbiology
Kidney - embryology
Kidney - microbiology
Nose - embryology
Nose - microbiology
Organ Culture Techniques
Singapore
Trachea - embryology
Trachea - microbiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223
cites cdi_FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223
container_end_page 711
container_issue 9
container_start_page 706
container_title Journal of clinical pathology
container_volume 26
creator Higgins, P. G.
Scott, R. J. D.
description In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the second outbreak which was isolated in organ cultures of conjunctiva. The virus associated with a third outbreak had previously been isolated from the original material by culture in human embryo kidney cells, but it required passage in organ culture for its detection after the specimens had been diluted.
doi_str_mv 10.1136/jcp.26.9.706
format article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_477856</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3970968721</sourcerecordid><originalsourceid>FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223</originalsourceid><addsrcrecordid>eNp9kc1v1DAQxS0EKkvhxhUpEhJcyOLxZ3LooVqgRaoWDuXjNnK8DnVI4sVOVuW_x9WuVpQDJ4_0fjN-M4-Q50CXAFy97ex2ydSyXmqqHpAFCM1KAUI9JAtKGZS1FuoxeZJSRylwDfyEnAguldRiQc6vb1zhU-jN5MNYhLZw4-Ri2Pk4J5eKNoahsOauzJqx8-QKG8ZuHu3kd37y6Sl51Jo-uWeH95R8-fD-enVZXn26-Lg6vyobodVUcmUZSNEY4EZKzlpGnVGtoAJASdEaXrVaKQOMVhteN43JdTbZyHpDK8b4KTnbz93OzeA2NvuMpsdt9IOJvzEYj_eV0d_gj7BDoXUlVe5_deiP4dfs0oSDT9b1vRldmBNWjOZD1ZDBl_-AXZjjmHdD0JryWlOQmXqzp2wMKUXXHp0AxbtcMOeCTGGNOZeMv_jb_RE-BJH1cq_7NLnbo2ziT1Saa4nrryus3qlv68_fGa4z_3rPN0P3_5__AP6SpJk</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1770397015</pqid></control><display><type>article</type><title>The isolation of enteroviruses from cases of acute conjunctivitis</title><source>PubMed Central</source><creator>Higgins, P. G. ; Scott, R. J. D.</creator><creatorcontrib>Higgins, P. G. ; Scott, R. J. D.</creatorcontrib><description>In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the second outbreak which was isolated in organ cultures of conjunctiva. The virus associated with a third outbreak had previously been isolated from the original material by culture in human embryo kidney cells, but it required passage in organ culture for its detection after the specimens had been diluted.</description><identifier>ISSN: 0021-9746</identifier><identifier>EISSN: 1472-4146</identifier><identifier>DOI: 10.1136/jcp.26.9.706</identifier><identifier>PMID: 4356574</identifier><identifier>CODEN: JCPAAK</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and Association of Clinical Pathologists</publisher><subject>Animals ; Conjunctivitis - diagnosis ; Conjunctivitis - microbiology ; Embryo, Mammalian ; England ; Enterovirus - isolation &amp; purification ; Epithelium - embryology ; Epithelium - microbiology ; Haplorhini ; Humans ; Indonesia ; Intestines - embryology ; Intestines - microbiology ; Kidney - embryology ; Kidney - microbiology ; Nose - embryology ; Nose - microbiology ; Organ Culture Techniques ; Singapore ; Trachea - embryology ; Trachea - microbiology</subject><ispartof>Journal of clinical pathology, 1973-09, Vol.26 (9), p.706-711</ispartof><rights>Copyright BMJ Publishing Group LTD Sep 1973</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223</citedby><cites>FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC477856/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC477856/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/4356574$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Higgins, P. G.</creatorcontrib><creatorcontrib>Scott, R. J. D.</creatorcontrib><title>The isolation of enteroviruses from cases of acute conjunctivitis</title><title>Journal of clinical pathology</title><addtitle>J Clin Pathol</addtitle><description>In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the second outbreak which was isolated in organ cultures of conjunctiva. The virus associated with a third outbreak had previously been isolated from the original material by culture in human embryo kidney cells, but it required passage in organ culture for its detection after the specimens had been diluted.</description><subject>Animals</subject><subject>Conjunctivitis - diagnosis</subject><subject>Conjunctivitis - microbiology</subject><subject>Embryo, Mammalian</subject><subject>England</subject><subject>Enterovirus - isolation &amp; purification</subject><subject>Epithelium - embryology</subject><subject>Epithelium - microbiology</subject><subject>Haplorhini</subject><subject>Humans</subject><subject>Indonesia</subject><subject>Intestines - embryology</subject><subject>Intestines - microbiology</subject><subject>Kidney - embryology</subject><subject>Kidney - microbiology</subject><subject>Nose - embryology</subject><subject>Nose - microbiology</subject><subject>Organ Culture Techniques</subject><subject>Singapore</subject><subject>Trachea - embryology</subject><subject>Trachea - microbiology</subject><issn>0021-9746</issn><issn>1472-4146</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1973</creationdate><recordtype>article</recordtype><recordid>eNp9kc1v1DAQxS0EKkvhxhUpEhJcyOLxZ3LooVqgRaoWDuXjNnK8DnVI4sVOVuW_x9WuVpQDJ4_0fjN-M4-Q50CXAFy97ex2ydSyXmqqHpAFCM1KAUI9JAtKGZS1FuoxeZJSRylwDfyEnAguldRiQc6vb1zhU-jN5MNYhLZw4-Ri2Pk4J5eKNoahsOauzJqx8-QKG8ZuHu3kd37y6Sl51Jo-uWeH95R8-fD-enVZXn26-Lg6vyobodVUcmUZSNEY4EZKzlpGnVGtoAJASdEaXrVaKQOMVhteN43JdTbZyHpDK8b4KTnbz93OzeA2NvuMpsdt9IOJvzEYj_eV0d_gj7BDoXUlVe5_deiP4dfs0oSDT9b1vRldmBNWjOZD1ZDBl_-AXZjjmHdD0JryWlOQmXqzp2wMKUXXHp0AxbtcMOeCTGGNOZeMv_jb_RE-BJH1cq_7NLnbo2ziT1Saa4nrryus3qlv68_fGa4z_3rPN0P3_5__AP6SpJk</recordid><startdate>19730901</startdate><enddate>19730901</enddate><creator>Higgins, P. G.</creator><creator>Scott, R. J. D.</creator><general>BMJ Publishing Group Ltd and Association of Clinical Pathologists</general><general>BMJ Publishing Group LTD</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19730901</creationdate><title>The isolation of enteroviruses from cases of acute conjunctivitis</title><author>Higgins, P. G. ; Scott, R. J. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1973</creationdate><topic>Animals</topic><topic>Conjunctivitis - diagnosis</topic><topic>Conjunctivitis - microbiology</topic><topic>Embryo, Mammalian</topic><topic>England</topic><topic>Enterovirus - isolation &amp; purification</topic><topic>Epithelium - embryology</topic><topic>Epithelium - microbiology</topic><topic>Haplorhini</topic><topic>Humans</topic><topic>Indonesia</topic><topic>Intestines - embryology</topic><topic>Intestines - microbiology</topic><topic>Kidney - embryology</topic><topic>Kidney - microbiology</topic><topic>Nose - embryology</topic><topic>Nose - microbiology</topic><topic>Organ Culture Techniques</topic><topic>Singapore</topic><topic>Trachea - embryology</topic><topic>Trachea - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Higgins, P. G.</creatorcontrib><creatorcontrib>Scott, R. J. D.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of clinical pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Higgins, P. G.</au><au>Scott, R. J. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The isolation of enteroviruses from cases of acute conjunctivitis</atitle><jtitle>Journal of clinical pathology</jtitle><addtitle>J Clin Pathol</addtitle><date>1973-09-01</date><risdate>1973</risdate><volume>26</volume><issue>9</issue><spage>706</spage><epage>711</epage><pages>706-711</pages><issn>0021-9746</issn><eissn>1472-4146</eissn><coden>JCPAAK</coden><abstract>In two epidemics of acute enterovirus conjunctivitis the diagnosis could only be established by the use of human embryonic organ cultures. In one instance cultures of ciliated respiratory epithelium proved sensitive to the virus but similar culture failed to support growth of the virus from the second outbreak which was isolated in organ cultures of conjunctiva. The virus associated with a third outbreak had previously been isolated from the original material by culture in human embryo kidney cells, but it required passage in organ culture for its detection after the specimens had been diluted.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and Association of Clinical Pathologists</pub><pmid>4356574</pmid><doi>10.1136/jcp.26.9.706</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0021-9746
ispartof Journal of clinical pathology, 1973-09, Vol.26 (9), p.706-711
issn 0021-9746
1472-4146
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_477856
source PubMed Central
subjects Animals
Conjunctivitis - diagnosis
Conjunctivitis - microbiology
Embryo, Mammalian
England
Enterovirus - isolation & purification
Epithelium - embryology
Epithelium - microbiology
Haplorhini
Humans
Indonesia
Intestines - embryology
Intestines - microbiology
Kidney - embryology
Kidney - microbiology
Nose - embryology
Nose - microbiology
Organ Culture Techniques
Singapore
Trachea - embryology
Trachea - microbiology
title The isolation of enteroviruses from cases of acute conjunctivitis
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T21%3A06%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20isolation%20of%20enteroviruses%20from%20cases%20of%20acute%20conjunctivitis&rft.jtitle=Journal%20of%20clinical%20pathology&rft.au=Higgins,%20P.%20G.&rft.date=1973-09-01&rft.volume=26&rft.issue=9&rft.spage=706&rft.epage=711&rft.pages=706-711&rft.issn=0021-9746&rft.eissn=1472-4146&rft.coden=JCPAAK&rft_id=info:doi/10.1136/jcp.26.9.706&rft_dat=%3Cproquest_pubme%3E3970968721%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b476t-36c2154ba13a5532f20ea6f40411654fa38f766a1208d39bba6a1565b59d08223%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1770397015&rft_id=info:pmid/4356574&rfr_iscdi=true