Concomitant Thyroid Disorders and Inflammatory Bowel Disease: A Literature Review

• Published in: BioMed research international 2016-01, Vol.2016 (2016), p.1-12
• Main Author: Shizuma, Toru
• Format: Article
• Language: English
• Subjects: Asian literature; Autoimmune diseases; Autoimmune Diseases - epidemiology; Autoimmune Diseases - immunology; Autoimmune Diseases - pathology; Colitis, Ulcerative - epidemiology; Colitis, Ulcerative - immunology; Colitis, Ulcerative - pathology; Congenital diseases; Crohn Disease - epidemiology; Crohn Disease - immunology; Crohn Disease - pathology; Crohn's disease; Graves Disease - epidemiology; Graves Disease - immunology; Graves Disease - pathology; Hashimoto Disease - epidemiology; Hashimoto Disease - immunology; Hashimoto Disease - pathology; Humans; Hyperthyroidism; Hypothyroidism; Inflammatory bowel disease; Inflammatory Bowel Diseases - epidemiology; Inflammatory Bowel Diseases - immunology; Inflammatory Bowel Diseases - pathology; Iodine; Literature reviews; Population; Review; Studies; Thyroid cancer; Thyroid diseases; Thyroid Diseases - epidemiology; Thyroid Diseases - immunology; Thyroid Diseases - pathology; Thyroid hormones; Thyroid Neoplasms - epidemiology; Thyroid Neoplasms - immunology; Thyroid Neoplasms - pathology; Ulcerative colitis
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2016/5187061

The aim of this report was to review and summarize the literature on cases of concomitant inflammatory bowel disease (IBD) and thyroid diseases. We included the following previous case reports of concomitant IBD and thyroid diseases: 16 cases of ulcerative colitis (UC) and Graves’ disease (GD), 3 cases of Crohn’s disease (CD) and GD, 10 cases of CD and Hashimoto’s thyroiditis (HT), 4 cases of IBD and subacute thyroiditis (SAT) or SAT-like symptoms, and 13 cases of IBD (12/13 cases were CD) and amyloid goiter. There might be no obvious differences of prevalence of thyroid dysfunction (hyper- or hypothyroidism), GD, and thyroid cancer between IBD patients and general populations. However, concomitant UC and HT might be relatively common in patients with multiple autoimmune disorders, and AG is one of the complications with CD patients. There might be no obvious differences of fatal prognoses between IBD patients with thyroid diseases and patients with thyroid diseases without IBD.