3D-printed guiding templates for improved osteosarcoma resection

Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-s...

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Bibliographic Details
Published in:Scientific reports 2016-03, Vol.6 (1), p.23335-23335, Article 23335
Main Authors: Ma, Limin, Zhou, Ye, Zhu, Ye, Lin, Zefeng, Wang, Yingjun, Zhang, Yu, Xia, Hong, Mao, Chuanbin
Format: Article
Language:English
Subjects:
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Adolescent
Adult
Bone cancer
Bone implants
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - surgery
Bone surgery
Bone Transplantation
Child
Computed tomography
Computer-Aided Design
Female
Follow-Up Studies
Humanities and Social Sciences
Humans
Imaging, Three-Dimensional
Magnetic resonance imaging
Male
multidisciplinary
NMR
Nuclear magnetic resonance
Organ Sparing Treatments
Osteosarcoma
Osteosarcoma - diagnostic imaging
Osteosarcoma - surgery
Printing
Printing, Three-Dimensional
Sarcoma
Science
Surgery, Computer-Assisted
Treatment Outcome
Tumors
Young Adult
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Summary:Osteosarcoma resection is challenging due to the variable location of tumors and their proximity with surrounding tissues. It also carries a high risk of postoperative complications. To overcome the challenge in precise osteosarcoma resection, computer-aided design (CAD) was used to design patient-specific guiding templates for osteosarcoma resection on the basis of the computer tomography (CT) scan and magnetic resonance imaging (MRI) of the osteosarcoma of human patients. Then 3D printing technique was used to fabricate the guiding templates. The guiding templates were used to guide the osteosarcoma surgery, leading to more precise resection of the tumorous bone and the implantation of the bone implants, less blood loss, shorter operation time and reduced radiation exposure during the operation. Follow-up studies show that the patients recovered well to reach a mean Musculoskeletal Tumor Society score of 27.125.
ISSN:2045-2322
2045-2322
DOI:10.1038/srep23335