Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?

Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin'...

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Bibliographic Details
Published in:Journal of intercultural ethnopharmacology 2016-01, Vol.5 (1), p.105-107
Main Authors: Akyol, Sumeyya, Gulec, Mehmet Akif, Erdemli, Haci Kemal, Akyol, Omer
Format: Article
Language:English
Subjects:
Mini Review
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Summary:Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin's and non-Hodgkin's lymphoma, Burkitt's lymphoma, chronic lymphocytic leukemia, Ewing's sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.
ISSN:2146-8397
2146-8397
DOI:10.5455/jice.20160127024542