The diagnostic value of serum leucine aminopeptidase

Serum leucine aminopeptidase determination was found to be a useful screening procedure for hepatobiliary disease in jaundiced and unjaundiced patients. Values under 1,000 units are of no help in the differential diagnosis of jaundice but values above 1,000 units are highly indicative of biliary obs...

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Bibliographic Details
Published in:Journal of clinical pathology 1964-01, Vol.17 (1), p.52-55
Main Authors: Mericas, G., Anagnostou, E., Hadziyannis, St, Kakari, S.
Format: Article
Language:English
Subjects:
Adolescent
Aminopeptidases
Chemical and Drug Induced Liver Injury
Child
Cholecystitis
Cholelithiasis
Clinical Enzyme Tests
Gallstones
Geriatrics
Hepatitis
Hepatitis A
Jaundice
Jaundice, Obstructive
Leucine
Leucyl Aminopeptidase
Liver Neoplasms
Neoplasm Metastasis
Pancreatic Neoplasms
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Summary:Serum leucine aminopeptidase determination was found to be a useful screening procedure for hepatobiliary disease in jaundiced and unjaundiced patients. Values under 1,000 units are of no help in the differential diagnosis of jaundice but values above 1,000 units are highly indicative of biliary obstruction. The differentiation of intra- from extrahepatic obstruction as well as of malignant from benign jaundice cannot generally be established by this single test.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.17.1.52