Vitamin Status among Breastfed Infants in Bhaktapur, Nepal

Vitamin deficiencies are known to be common among infants residing in low- and middle-income countries but relatively few studies have assessed several biochemical parameters simultaneously. The objective of the study was to describe the status of vitamins (A, D, E, B₆, B12 and folate) in breastfed...

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Bibliographic Details
Published in:Nutrients 2016-03, Vol.8 (3), p.149-149
Main Authors: Ulak, Manjeswori, Chandyo, Ram K, Thorne-Lyman, Andrew L, Henjum, Sigrun, Ueland, Per M, Midttun, Øivind, Shrestha, Prakash S, Fawzi, Wafaie W, Graybill, Lauren, Strand, Tor A
Format: Article
Language:English
Subjects:
Acids
Adult
Age Factors
alpha-tocopherol
Avitaminosis - blood
Avitaminosis - diagnosis
Avitaminosis - epidemiology
Avitaminosis - physiopathology
Babies
Biomarkers
Biomarkers - blood
Breast Feeding
Breastfeeding & lactation
C-reactive protein
children
Cognitive development
Dietary minerals
Dietary Supplements
Female
folic acid
food fortification
Food, Fortified
Health Surveys
hemoglobin
Homocysteine
Humans
Infant
Infant Nutritional Physiological Phenomena
infants
Male
methylmalonic acid
Mothers
Nepal
Nepal - epidemiology
Nutrients
Nutrition Assessment
Nutritional Status
Plasma
Prevalence
Public health
pyridoxal
pyridoxal phosphate
Socioeconomic Factors
Vitamin A
Vitamin B
vitamin B12
Vitamin D
vitamin deficiencies
Vitamin E
vitamin status
Vitamins - administration & dosage
Vitamins - blood
women
Young Adult
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Summary:Vitamin deficiencies are known to be common among infants residing in low- and middle-income countries but relatively few studies have assessed several biochemical parameters simultaneously. The objective of the study was to describe the status of vitamins (A, D, E, B₆, B12 and folate) in breastfed infants. We measured the plasma concentrations of trans retinol, 25 hydroxy vitamin D, α-tocopherol, pyridoxal 5'-phosphate, cobalamin, folate, methylmalonic acid, homocysteine, hemoglobin and C-reactive protein from 467 randomly selected infants. One in five (22%) was deficient in at least one vitamin. Mean (SD) plasma folate concentration was 73 (35) nmol/L, and no infant in the sample was folate deficient. Vitamin B₆ deficiency and vitamin B12 deficiency was found in 22% and 17% of the infants, respectively. Elevated plasma methylmalonic acid or total homocysteine concentration was found in 82% and 62% of infants, respectively. Fifteen percent of infants were vitamin A deficient and 65% were marginally deficient in vitamin A. Fewer than 5% of infants had low plasma vitamin D concentration or vitamin E concentration (α-tocopherol
ISSN:2072-6643
2072-6643
DOI:10.3390/nu8030149