Direct Observation of Early-Stage High-Dose Radiotherapy-Induced Vascular Injury via Basement Membrane-Targeting Nanoparticles

Collagen IV‐targeting peptide‐conjugated basement membrane‐targeting nanoparticles are successfully engineered to identify early‐stage blood vessel injury induced by high‐dose radiotherapy.

Saved in:
Bibliographic Details
Published in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2015-12, Vol.11 (48), p.6404-6410
Main Authors: Au, Kin Man, Hyder, Sayed Nabeel, Wagner, Kyle, Shi, Caihong, Kim, Young Seok, Caster, Joseph M., Tian, Xi, Min, Yuanzeng, Wang, Andrew Z.
Format: Article
Language:English
Subjects:
Animals
Basement Membrane - drug effects
Basement Membrane - metabolism
basement membrane-targeting nanoparticles
cancer
cardiovascular disease
Collagen Type IV - pharmacology
Dose-Response Relationship, Radiation
Fluorescence
Lactic Acid - chemistry
medical imaging
Mice, Nude
Nanoparticles - chemistry
Nanotechnology
Optical Imaging
Polyethylene Glycols - chemistry
Polyglycolic Acid - chemistry
Polylactic Acid-Polyglycolic Acid Copolymer
Radiation Injuries - diagnosis
radiotherapy
Radiotherapy - adverse effects
Vascular System Injuries - diagnosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Collagen IV‐targeting peptide‐conjugated basement membrane‐targeting nanoparticles are successfully engineered to identify early‐stage blood vessel injury induced by high‐dose radiotherapy.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.201501902