Platelet-Rich Blood Derivatives for Stem Cell-Based Tissue Engineering and Regeneration

Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails of autologous growth factors, which could provide an alternative for recombinant protein-based approaches. Platelet-rich blood derivatives, s...

Full description

Saved in:
Bibliographic Details
Published in:Current stem cell reports 2016-03, Vol.2 (1), p.33-42
Main Authors: Masoudi, Elham A., Ribas, João, Kaushik, Gaurav, Leijten, Jeroen, Khademhosseini, Ali
Format: Article
Language:English
Subjects:
Autografts
Biomedical and Life Sciences
Biomedical Engineering/Biotechnology
Biomedicine
Blood
Blood platelets
Cell Biology
Cell differentiation
Cell migration
Cell proliferation
Gene Therapy
Growth factors
Immunology
Life Sciences
Platelets
Regenerative medicine
Section Editor
Stem Cells
Stem Cells and Nanotechnologies (T Kyriakides
Tissue engineering
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Platelet-rich blood derivatives have been widely used in different fields of medicine and stem cell-based tissue engineering. They represent natural cocktails of autologous growth factors, which could provide an alternative for recombinant protein-based approaches. Platelet-rich blood derivatives, such as platelet-rich plasma, have consistently shown to potentiate stem cell proliferation, migration, and differentiation. Here, we review the spectrum of platelet-rich blood derivatives, discuss their current applications in tissue engineering and regenerative medicine, reflect on their effect on stem cells, and highlight current translational challenges.
ISSN:2198-7866
2198-7866
DOI:10.1007/s40778-016-0034-8