An Overview of the Diagnosis and Management of Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa. The diagnosis requires esophageal biopsies demonstrating at least 15 eosinophils per high-powered field following a course of...

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Bibliographic Details
Published in:Clinical and translational gastroenterology 2016-03, Vol.7 (3), p.e155-e155
Main Authors: Singla, Manish B, Moawad, Fouad J
Format: Article
Language:English
Subjects:
Clinical and Systematic Reviews
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Summary:Eosinophilic esophagitis (EoE) is a chronic inflammatory condition characterized by symptoms of esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa. The diagnosis requires esophageal biopsies demonstrating at least 15 eosinophils per high-powered field following a course of high-dose proton pump inhibitors. Management of EoE consists of the three Ds: drugs, dietary therapy, and esophageal dilation. In this review, we discuss the epidemiology, pathogenesis, diagnosis, and treatment of EoE to include the role of emerging therapies.
ISSN:2155-384X
2155-384X
DOI:10.1038/ctg.2016.4