Kalium: a database of potassium channel toxins from scorpion venom

• Published in: Database : the journal of biological databases and curation 2016, Vol.2016, p.baw056
• Main Authors: Kuzmenkov, Alexey I, Krylov, Nikolay A, Chugunov, Anton O, Grishin, Eugene V, Vassilevski, Alexander A
• Format: Article
• Language: English
• Subjects: Animals; Databases, Protein; Humans; Internet; Original; Potassium Channel Blockers - chemistry; Potassium Channels - chemistry; Scorpion Venoms - chemistry
• ISSN: 1758-0463; 1758-0463
• DOI: 10.1093/database/baw056

Kalium (http://kaliumdb.org/) is a manually curated database that accumulates data on potassium channel toxins purified from scorpion venom (KTx). This database is an open-access resource, and provides easy access to pages of other databases of interest, such as UniProt, PDB, NCBI Taxonomy Browser, and PubMed. General achievements of Kalium are a strict and easy regulation of KTx classification based on the unified nomenclature supported by researchers in the field, removal of peptides with partial sequence and entries supported by transcriptomic information only, classification of β-family toxins, and addition of a novel λ-family. Molecules presented in the database can be processed by the Clustal Omega server using a one-click option. Molecular masses of mature peptides are calculated and available activity data are compiled for all KTx. We believe that Kalium is not only of high interest to professional toxinologists, but also of general utility to the scientific community.Database URL:http://kaliumdb.org/.