A Novel Technique to Treat Air Leak Following Lobectomy: Intrapleural Infusion of Plasma

BACKGROUND Persistent air leak following pulmonary lobectomy can be very difficult to treat and results in prolonged hospitalization. We aimed to evaluate the efficacy of a new method of postoperative air leak management using intrapleurally infused fresh frozen plasma via the chest tube. MATERIAL A...

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Bibliographic Details
Published in:Medical science monitor 2016-04, Vol.22, p.1258-1264
Main Authors: Konstantinou, Froso, Potaris, Konstantinos, Syrigos, Konstantinos N, Tsipas, Panteleimon, Karagkiouzis, Grigorios, Konstantinou, Marios
Format: Article
Language:English
Subjects:
Aged
Blood Transfusion - methods
Chest Tubes
Clinical Research
Female
Freezing
Humans
Lung Neoplasms - surgery
Male
Middle Aged
Plasma
Pneumothorax - etiology
Pneumothorax - therapy
Postoperative Complications - etiology
Postoperative Complications - therapy
Retrospective Studies
Thoracic Surgical Procedures - methods
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Summary:BACKGROUND Persistent air leak following pulmonary lobectomy can be very difficult to treat and results in prolonged hospitalization. We aimed to evaluate the efficacy of a new method of postoperative air leak management using intrapleurally infused fresh frozen plasma via the chest tube. MATERIAL AND METHODS Between June 2008 and June 2014, we retrospectively reviewed 98 consecutive patients who underwent lobectomy for lung cancer and postoperatively developed persistent air leak treated with intrapleural instillation of fresh frozen plasma. RESULTS The study identified 89 men and 9 women, with a median age of 65.5 years (range 48-77 years), with persistent postoperative air leak. Intrapleural infusion of fresh frozen plasma was successful in stopping air leaks in 90 patients (92%) within 24 hours, and in 96 patients (98%) within 48 hours, following resumption of the procedure. In the remaining 2, air leak ceased at 14 and 19 days. CONCLUSIONS Intrapleural infusion of fresh frozen plasma is a safe, inexpensive, and remarkably effective method for treatment of persistent air leak following lobectomy for lung cancer.
ISSN:1643-3750
1234-1010
1643-3750
DOI:10.12659/MSM.895134