Chlamydia trachomatis Infection in Pregnancy: The Global Challenge of Preventing Adverse Pregnancy and Infant Outcomes in Sub-Saharan Africa and Asia

Screening and treatment of sexually transmitted infections (STIs) in pregnancy represents an overlooked opportunity to improve the health outcomes of women and infants worldwide. Although Chlamydia trachomatis is the most common treatable bacterial STI, few countries have routine pregnancy screening...

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Bibliographic Details
Published in:BioMed research international 2016-01, Vol.2016 (2016), p.1-21
Main Authors: Adachi, Kristina, Klausner, Jeffrey D., Nielsen-Saines, Karin
Format: Article
Language:English
Subjects:
Africa South of the Sahara - epidemiology
Age
Asia
Babies
Care and treatment
Children & youth
Chlamydia
Chlamydia infections
Chlamydia Infections - mortality
Chlamydia Infections - prevention & control
Chlamydia trachomatis
Condoms
Disease transmission
Female
Fetuses
Global Health - trends
Health aspects
Health Promotion - trends
HIV
Human immunodeficiency virus
Humans
Infant, Newborn
Infant, Newborn, Diseases - mortality
Infant, Newborn, Diseases - prevention & control
Infants (Premature)
Infections
Infectious Disease Transmission, Vertical - prevention & control
Infectious Disease Transmission, Vertical - statistics & numerical data
Male
Miscarriage
Mortality
Pregnancy
Pregnancy Complications, Infectious - mortality
Pregnancy Complications, Infectious - prevention & control
Pregnancy Outcome - epidemiology
Pregnant women
Premature birth
Prenatal care
Prevalence
Prevention
Reproductive health
Review
Risk Assessment
Stillbirth
Studies
Survival Rate
Vaccines
Women
Womens health
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Description
Summary:Screening and treatment of sexually transmitted infections (STIs) in pregnancy represents an overlooked opportunity to improve the health outcomes of women and infants worldwide. Although Chlamydia trachomatis is the most common treatable bacterial STI, few countries have routine pregnancy screening and treatment programs. We reviewed the current literature surrounding Chlamydia trachomatis in pregnancy, particularly focusing on countries in sub-Saharan Africa and Asia. We discuss possible chlamydial adverse pregnancy and infant health outcomes (miscarriage, stillbirth, ectopic pregnancy, preterm birth, neonatal conjunctivitis, neonatal pneumonia, and other potential effects including HIV perinatal transmission) and review studies of chlamydial screening and treatment in pregnancy, while simultaneously highlighting research from resource-limited countries in sub-Saharan Africa and Asia.
ISSN:2314-6133
2314-6141
DOI:10.1155/2016/9315757