Cystic renal cell carcinoma carries an excellent prognosis regardless of tumor size

Abstract Introduction Cystic renal cell carcinoma (cystic RCC) is thought to carry an improved prognosis relative to clear cell RCC (CCRCC); however, this is based on small case series. We used a population-based tumor registry to compare clinicopathologic features and cancer-specific mortality (CSM...

Full description

Saved in:
Bibliographic Details
Published in:Urologic oncology 2015-12, Vol.33 (12), p.505.e9-505.e13
Main Authors: Winters, Brian R., M.D, Gore, John L., M.D., M.S, Holt, Sarah K., Ph.D, Harper, Jonathan D., M.D, Lin, Daniel W., M.D, Wright, Jonathan L., M.D., M.S
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Carcinoma, Renal Cell - diagnosis
Carcinoma, Renal Cell - mortality
Carcinoma, Renal Cell - pathology
Clear cell RCC
Cystic RCC
Female
Humans
Male
Middle Aged
Neoplasm Staging
Prognosis
Renal cell carcinoma
Survival
Survival Analysis
Urology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Introduction Cystic renal cell carcinoma (cystic RCC) is thought to carry an improved prognosis relative to clear cell RCC (CCRCC); however, this is based on small case series. We used a population-based tumor registry to compare clinicopathologic features and cancer-specific mortality (CSM) of cystic RCC with those of CCRCC. Materials and methods The Surveillance, Epidemiology, and End Results database was queried for all patients diagnosed and treated for cystic RCC and CCRCC between 2001 and 2010. Clinical and pathologic factors were compared using t tests and chi-square tests as appropriate. Kaplan-Meier survival analysis compared CSM differences between cystic RCC and CCRCC. Results A total of 678 patients with cystic RCC and 46,677 with CCRCC were identified. The mean follow-up duration was 52 and 40 months, respectively. When compared with CCRCC patients, those with cystic RCC were younger (mean age 58 vs. 61 y, P
ISSN:1078-1439
1873-2496
DOI:10.1016/j.urolonc.2015.07.017