Does measurement of four-limb blood pressures at birth improve detection of aortic arch anomalies?

• Published in: Journal of perinatology 2016-05, Vol.36 (5), p.376-380
• Main Authors: Patankar, N, Fernandes, N, Kumar, K, Manja, V, Lakshminrusimha, S
• Format: Article
• Language: English
• Subjects: 631/443/592; 692/699/75/1539; Analysis; Anomalies; Aorta; Aorta, Thoracic - abnormalities; Aortic arch; Aortic Coarctation - diagnosis; Aortic Coarctation - physiopathology; Birth; Blood pressure; Blood Pressure - physiology; Blood Pressure Determination - methods; Cardiovascular Abnormalities - diagnosis; Cardiovascular Abnormalities - physiopathology; Cardiovascular disease; Cardiovascular diseases; Care and treatment; Case-Control Studies; Congenital diseases; Congenital heart disease; Coronary artery disease; Coronary vessels; Diagnosis; Female; Genetic disorders; Gestational age; Heart; Heart diseases; Hospitals; Humans; Infant, Newborn; Intensive care; Lower Extremity - blood supply; Male; Medicine; Medicine & Public Health; Neonatal Screening; Neonates; Newborn babies; original-article; Pediatric Surgery; Pediatrics; Reproducibility of Results; Retrospective Studies; Sensitivity and Specificity; United States; Upper Extremity - blood supply
• ISSN: 0743-8346; 1476-5543
• DOI: 10.1038/jp.2015.203

Objective: To determine normal four-extremity blood pressure (BP) in the neonatal intensive care unit (NICU) at birth and the utility of upper (UE) and lower extremity (LE) BP difference to screen for coarctation of the aorta (Co-A) and interrupted the aortic arch (IAA). Study Design: Retrospective study of BP at birth ( n =866), and case–control study of Co-A/IAA infants and matched controls (1:2). Result: Although BP increased with gestational age ( R 2 =0.3, P