Involvement of advanced glycation end‐products in ‘hyperglycemic memory’

The series of reports by the DCCT Skin Collagen Ancillary Study Group are very interesting and informative. The hypothesis from these reports clearly indicates that AGEs are a strong candidate for the mechanism of the ‘hyperglycemic memory.’

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Bibliographic Details
Published in:Journal of diabetes investigation 2016-05, Vol.7 (3), p.297-299
Main Authors: Nishikawa, Takeshi, Araki, Eiichi
Format: Article
Language:English
Subjects:
Advanced glycosylation end products
Animals
Biopsy
Collagen
Commentaries
Diabetes
Diabetes Complications - metabolism
Diabetes mellitus
Diabetic retinopathy
Glucose
Glycation End Products, Advanced - metabolism
Humans
Hyperglycemia
Hyperglycemia - complications
Hyperglycemia - metabolism
Hypotheses
Insulin
Kinases
Metabolism
Microvasculature
Oxidative stress
Pathogenesis
Proteins
Retinopathy
Skin
Studies
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Description
Summary:The series of reports by the DCCT Skin Collagen Ancillary Study Group are very interesting and informative. The hypothesis from these reports clearly indicates that AGEs are a strong candidate for the mechanism of the ‘hyperglycemic memory.’
ISSN:2040-1116
2040-1124
DOI:10.1111/jdi.12405