Design, development and validation of a new laryngo-pharyngeal endoscopic esthesiometer and range-finder based on the assessment of air-pulse variability determinants

Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associated with a wide range of airway reflex abnormalities. However, the current device for explorin...

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Bibliographic Details
Published in:Biomedical engineering online 2016-05, Vol.15 (1), p.52-52, Article 52
Main Authors: Giraldo-Cadavid, Luis F, Agudelo-Otalora, Luis Mauricio, Burguete, Javier, Arbulu, Mario, Moscoso, William Daniel, Martínez, Fabio, Ortiz, Andrés Felipe, Diaz, Juan, Pantoja, Jaime A, Rueda-Arango, Andrés Felipe, Fernández, Secundino
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Air
Care and treatment
Diagnosis
Endoscopy
Endoscopy - instrumentation
Equipment and supplies
Equipment Design
Female
Fiber optics
Humans
Laryngeal diseases
Larynx - physiology
Male
Methods
Middle Aged
Pharynx - physiology
Pressure
Reflex
Sensation
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Summary:Laryngo-pharyngeal mechano-sensitivity (LPMS) is involved in dysphagia, sleep apnea, stroke, irritable larynx syndrome and cough hypersensitivity syndrome among other disorders. These conditions are associated with a wide range of airway reflex abnormalities. However, the current device for exploring LPMS is limited because it assesses only the laryngeal adductor reflex during fiber-optic endoscopic evaluations of swallowing and requires a high degree of expertise to obtain reliable results, introducing intrinsic expert variability and subjectivity. We designed, developed and validated a new air-pulse laryngo-pharyngeal endoscopic esthesiometer with a built-in laser range-finder (LPEER) based on the evaluation and control of air-pulse variability determinants and on intrinsic observer variability and subjectivity determinants of the distance, angle and site of stimulus impact. The LPEER was designed to be capable of delivering precise and accurate stimuli with a wide range of intensities that can explore most laryngo-pharyngeal reflexes. We initially explored the potential factors affecting the reliability of LPMS tests and included these factors in a multiple linear regression model. The following factors significantly affected the precision and accuracy of the test (P 
ISSN:1475-925X
1475-925X
DOI:10.1186/s12938-016-0166-1