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Predominance of Movement Speed Over Direction in Neuronal Population Signals of Motor Cortex: Intracranial EEG Data and A Simple Explanatory Model
How neuronal activity of motor cortex is related to movement is a central topic in motor neuroscience. Motor-cortical single neurons are more closely related to hand movement velocity than speed, that is, the magnitude of the (directional) velocity vector. Recently, there is also increasing interest...
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Published in: | Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2016-06, Vol.26 (6), p.2863-2881 |
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container_title | Cerebral cortex (New York, N.Y. 1991) |
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creator | Hammer, Jiří Pistohl, Tobias Fischer, Jörg Kršek, Pavel Tomášek, Martin Marusič, Petr Schulze-Bonhage, Andreas Aertsen, Ad Ball, Tonio |
description | How neuronal activity of motor cortex is related to movement is a central topic in motor neuroscience. Motor-cortical single neurons are more closely related to hand movement velocity than speed, that is, the magnitude of the (directional) velocity vector. Recently, there is also increasing interest in the representation of movement parameters in neuronal population activity, such as reflected in the intracranial EEG (iEEG). We show that in iEEG, contrasting to what has been previously found on the single neuron level, speed predominates over velocity. The predominant speed representation was present in nearly all iEEG signal features, up to the 600-1000 Hz range. Using a model of motor-cortical signals arising from neuronal populations with realistic single neuron tuning properties, we show how this reversal can be understood as a consequence of increasing population size. Our findings demonstrate that the information profile in large population signals may systematically differ from the single neuron level, a principle that may be helpful in the interpretation of neuronal population signals in general, including, for example, EEG and functional magnetic resonance imaging. Taking advantage of the robust speed population signal may help in developing brain-machine interfaces exploiting population signals. |
doi_str_mv | 10.1093/cercor/bhw033 |
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Motor-cortical single neurons are more closely related to hand movement velocity than speed, that is, the magnitude of the (directional) velocity vector. Recently, there is also increasing interest in the representation of movement parameters in neuronal population activity, such as reflected in the intracranial EEG (iEEG). We show that in iEEG, contrasting to what has been previously found on the single neuron level, speed predominates over velocity. The predominant speed representation was present in nearly all iEEG signal features, up to the 600-1000 Hz range. Using a model of motor-cortical signals arising from neuronal populations with realistic single neuron tuning properties, we show how this reversal can be understood as a consequence of increasing population size. Our findings demonstrate that the information profile in large population signals may systematically differ from the single neuron level, a principle that may be helpful in the interpretation of neuronal population signals in general, including, for example, EEG and functional magnetic resonance imaging. Taking advantage of the robust speed population signal may help in developing brain-machine interfaces exploiting population signals.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Arm - physiology</subject><subject>Biomechanical Phenomena</subject><subject>Electrocorticography</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Models, Neurological</subject><subject>Motor Activity - physiology</subject><subject>Motor Cortex - physiology</subject><subject>Neurons - physiology</subject><subject>Neuropsychological Tests</subject><subject>Young Adult</subject><issn>1047-3211</issn><issn>1460-2199</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNqFkUtP3TAQha2qqNBblt1WXnaTXj8SO-4CCV1uKRIvibK2HGcCrhI7OMkF_kZ_cQ0BBCtWMxp_53hGB6GvlPygRPGlhWhDXFbXt4TzD2iH5oJkjCr1MfUklxlnlG6jz8PwlxAqWcE-oW0mVJmXqthB_84j1KFz3ngLODT4JGygAz_iix6gxmcbiPjARbCjCx47j09hisGbFp-HfmrN4_jCXaXJMOvHEPEqxBHufuIjP0Zjo_EuCdbrQ3xgRoONr_F-EnV9C3h917fGm6S6T-Ia2i9oq0lmsPtUF-jy1_rP6nd2fHZ4tNo_zmxeijGzUEipGrC5YBWvSFEVkoGhFhrFlaiFbEDWNSOG2EoylQurQEgAZSqiDOELtDf79lPVQW3hYddW99F1Jt7rYJx---Ldtb4KG52-VyUVyeD7k0EMNxMMo-7cYKFN50CYBk1LkkjCZPk-KlVKp-QFT2g2ozaGYYjQvGxEiX6IXM-R6znyxH97fcYL_Zwx_w9rr6zP</recordid><startdate>20160601</startdate><enddate>20160601</enddate><creator>Hammer, Jiří</creator><creator>Pistohl, Tobias</creator><creator>Fischer, Jörg</creator><creator>Kršek, Pavel</creator><creator>Tomášek, Martin</creator><creator>Marusič, Petr</creator><creator>Schulze-Bonhage, Andreas</creator><creator>Aertsen, Ad</creator><creator>Ball, Tonio</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope><scope>5PM</scope></search><sort><creationdate>20160601</creationdate><title>Predominance of Movement Speed Over Direction in Neuronal Population Signals of Motor Cortex: Intracranial EEG Data and A Simple Explanatory Model</title><author>Hammer, Jiří ; Pistohl, Tobias ; Fischer, Jörg ; Kršek, Pavel ; Tomášek, Martin ; Marusič, Petr ; Schulze-Bonhage, Andreas ; Aertsen, Ad ; Ball, Tonio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c486t-ce5779fec462b3b05b572ea1cef9396d67fe7dd20a0cb72946c9e67ee9ab09a03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Arm - physiology</topic><topic>Biomechanical Phenomena</topic><topic>Electrocorticography</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Models, Neurological</topic><topic>Motor Activity - physiology</topic><topic>Motor Cortex - physiology</topic><topic>Neurons - physiology</topic><topic>Neuropsychological Tests</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hammer, Jiří</creatorcontrib><creatorcontrib>Pistohl, Tobias</creatorcontrib><creatorcontrib>Fischer, Jörg</creatorcontrib><creatorcontrib>Kršek, Pavel</creatorcontrib><creatorcontrib>Tomášek, Martin</creatorcontrib><creatorcontrib>Marusič, Petr</creatorcontrib><creatorcontrib>Schulze-Bonhage, Andreas</creatorcontrib><creatorcontrib>Aertsen, Ad</creatorcontrib><creatorcontrib>Ball, Tonio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cerebral cortex (New York, N.Y. 1991)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hammer, Jiří</au><au>Pistohl, Tobias</au><au>Fischer, Jörg</au><au>Kršek, Pavel</au><au>Tomášek, Martin</au><au>Marusič, Petr</au><au>Schulze-Bonhage, Andreas</au><au>Aertsen, Ad</au><au>Ball, Tonio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Predominance of Movement Speed Over Direction in Neuronal Population Signals of Motor Cortex: Intracranial EEG Data and A Simple Explanatory Model</atitle><jtitle>Cerebral cortex (New York, N.Y. 1991)</jtitle><addtitle>Cereb Cortex</addtitle><date>2016-06-01</date><risdate>2016</risdate><volume>26</volume><issue>6</issue><spage>2863</spage><epage>2881</epage><pages>2863-2881</pages><issn>1047-3211</issn><eissn>1460-2199</eissn><abstract>How neuronal activity of motor cortex is related to movement is a central topic in motor neuroscience. 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subjects | Adolescent Adult Arm - physiology Biomechanical Phenomena Electrocorticography Female Humans Male Middle Aged Models, Neurological Motor Activity - physiology Motor Cortex - physiology Neurons - physiology Neuropsychological Tests Young Adult |
title | Predominance of Movement Speed Over Direction in Neuronal Population Signals of Motor Cortex: Intracranial EEG Data and A Simple Explanatory Model |
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