Breastmilk from obese mothers has pro-inflammatory properties and decreased neuroprotective factors

Objective: To determine the impact of maternal obesity on breastmilk composition. Study Design: Breastmilk and food records from 21 lean and 21 obese women who delivered full-term infants were analyzed at 2 months post-partum. Infant growth and adiposity were measured at birth and 2 months of age. R...

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Bibliographic Details
Published in:Journal of perinatology 2016-04, Vol.36 (4), p.284-290
Main Authors: Panagos, P G, Vishwanathan, R, Penfield-Cyr, A, Matthan, N R, Shivappa, N, Wirth, M D, Hebert, J R, Sen, S
Format: Article
Language:English
Subjects:
692/308/575
692/420/256/2515
Adipose tissue
Analysis
Body mass
Body Mass Index
Body size
Breast milk
Carotenoids
Case-Control Studies
Child Development
Diet
Docosahexaenoic acid
Eicosapentaenoic acid
Fatty acids
Fatty Acids - analysis
Female
Health aspects
Humans
Infant
Infant, Newborn
Infants
Inflammation
Lutein
Lutein - analysis
Medicine
Medicine & Public Health
Milk, Human - chemistry
Milk, Human - immunology
Mothers
Neurodevelopment
Neuroprotection
Obesity
Obesity - physiopathology
Omega-3 fatty acids
original-article
Pediatric Surgery
Pediatrics
Physical growth
Physiological aspects
Pregnancy
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Summary:Objective: To determine the impact of maternal obesity on breastmilk composition. Study Design: Breastmilk and food records from 21 lean and 21 obese women who delivered full-term infants were analyzed at 2 months post-partum. Infant growth and adiposity were measured at birth and 2 months of age. Result: Breastmilk from obese mothers had higher omega-6 to omega-3 fatty acid ratio and lower concentrations of docosahexaenoic acid, eicosapentaenoic acid, docasapentaenoic acid and lutein compared with lean mothers ( P
ISSN:0743-8346
1476-5543
DOI:10.1038/jp.2015.199