Platelet catecholamines in cluster headache

Platelet tyrosine and catecholamine (CA) content was measured in cluster headache sufferers during the different phases of the illness. Compared with controls, cluster headache sufferers had lower platelet levels of norepinephrine (NE) and epinephrine (E) in all phases of the syndrome. Tyrosine leve...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1992-04, Vol.55 (4), p.308-309
Main Authors: D'Andrea, G, Cananzi, A R, Morra, M, Martignoni, E, Fornasiero, S, Zamberlan, F, Grunfeld, S, Welch, K M
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Blood Platelets - metabolism
Cluster Headache - blood
Epinephrine - blood
Female
Humans
Male
Medical sciences
Middle Aged
Neurology
Norepinephrine - blood
Tyrosine - blood
Vascular diseases and vascular malformations of the nervous system
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Summary:Platelet tyrosine and catecholamine (CA) content was measured in cluster headache sufferers during the different phases of the illness. Compared with controls, cluster headache sufferers had lower platelet levels of norepinephrine (NE) and epinephrine (E) in all phases of the syndrome. Tyrosine levels were increased significantly during the cluster headache attack. We suggest that these results provide biochemical evidence of sympathetic nervous system (SNS) hypofunction in cluster headache.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.55.4.308